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Synthesis and antimicrobial activity of N-(4-chlorophenyl)-β-alanine derivatives with an azole moiety

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Abstract

N-(4-Chlorophenyl)-β-alanine was shown to be a useful synthetic intermediate for synthesis of azole heterocycles. Their structure was characterized by IR, mass, and NMR spectroscopy, and elemental analysis. Some of the synthesized compounds had antibacterial activity against Rhizobium radiobacter, as determined by use of the diffusion technique.

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Authors and Affiliations

  1. Department of Organic Chemistry, Kaunas University of Technology, Radvilėnų Pl. 19, LT-50254, Kaunas, Lithuania

    Kazimieras Anusevičius, Ilona Jonuškienė & Vytautas Mickevičius

Authors
  1. Kazimieras Anusevičius
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  2. Ilona Jonuškienė
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  3. Vytautas Mickevičius
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Correspondence to Ilona Jonuškienė.

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Anusevičius, K., Jonuškienė, I. & Mickevičius, V. Synthesis and antimicrobial activity of N-(4-chlorophenyl)-β-alanine derivatives with an azole moiety. Monatsh Chem 144, 1883–1891 (2013). https://doi.org/10.1007/s00706-013-1074-8

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  • DOI: https://doi.org/10.1007/s00706-013-1074-8

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