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Synthesis of novel halogenated 2-vinylchroman-4-ones and their antimicrobial activity

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Abstract

Novel halogenated 2-vinylchromanones were prepared which show a strong growth inhibition toward Gram-negative bacteria. The activity pattern is different to previously reported derivatives and depends on the position of the halogen substituent.

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Acknowledgments

Financial support by the State of Mecklenburg-Vorpommern is gratefully acknowledged. The work was supported by the European Union (EFRE program). The work was also supported by the TÁMOP-4.2.1/B-09/KONV-2010-007 project. The project is implemented through the New Hungary Development Plan, co-financed by the European Social Fund and the European Regional Development Fund.

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Authors and Affiliations

  1. Institut für Chemie, Universität Rostock, Albert Einstein Str. 3a, 18059, Rostock, Germany

    Friedrich Erben, Marcel Sonneck & Peter Langer

  2. Leibniz-Institut für Katalyse an der Universität Rostock e.V, Albert Einstein Str. 29a, 18059, Rostock, Germany

    Peter Langer

  3. Institut für Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald, F.-L.-Jahn-Str. 17, 17487, Greifswald, Germany

    Martina Wurster, Michael Lalk & Ulrike Lindequist

  4. Department of Organic Chemistry, University of Debrecen, Egyetem tér 1, 4032, Debrecen, Hungary

    Marcel Sonneck, Krisztina Kónya & Tamás Patonay

Authors
  1. Friedrich Erben
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  2. Martina Wurster
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  3. Michael Lalk
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  4. Ulrike Lindequist
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  5. Marcel Sonneck
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  6. Krisztina Kónya
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  7. Tamás Patonay
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  8. Peter Langer
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Corresponding author

Correspondence to Peter Langer.

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Erben, F., Wurster, M., Lalk, M. et al. Synthesis of novel halogenated 2-vinylchroman-4-ones and their antimicrobial activity. Monatsh Chem 144, 345–349 (2013). https://doi.org/10.1007/s00706-012-0891-5

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  • DOI: https://doi.org/10.1007/s00706-012-0891-5

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