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Low-dimensional compounds containing bioactive ligands. I: Crystal structure, spectroscopic, and thermal properties of the first row transition metal coordination compounds with clioquinol

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Abstract

Coordination compounds of first row transition metals from Mn to Zn with clioquinol (5-chloro-7-iodo-8-hydroxyquinoline, CQ) were prepared and characterized by infrared spectroscopy and thermal analysis. The composition of these compounds determined by elemental analysis is [M(CQ)2(H2O)2] for Mn and Zn, [M(CQ)2] for Fe, Co, Ni, and Cu, and NH2(CH3)2[Ni(CQ)3]·DMF·H2O (DMF = N,N-dimethylformamide). X-ray structure analysis revealed that the [Ni(CQ)2] complex is a molecular coordination compound with Ni(II) square-planarly coordinated by nitrogen and oxygen atoms of two trans-arranged bidentate molecules of clioquinol. On the other hand, NH2(CH3)2[Ni(CQ)3]·DMF·H2O is an ionic compound containing three clioquinol molecules coordinated to the central atom in a deformed octahedral geometry thus forming a complex anion. Its negative charge is balanced by the dimethylammonium cation and the structure also contains solvated water and DMF molecules. Long-range interactions and hydrogen bonds in these two complexes were also investigated.

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Acknowledgments

This work was supported by the ERDF EU (European Union European regional development fond) grant, under the contract No. ITMS26220120005 and by the internal P.J. Šafárik University grant VVGS PF 27/2011/CH. The authors are very grateful to Prof. Vladimír Zeleňák from P.J. Šafárik University in Košice for the thermal analysis measurements.

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  1. Department of Inorganic Chemistry, Institute of Chemistry, P. J. Šafárik University, Moyzesova 11, 04154, Košice, Slovakia

    Ivan Potočňák & Peter Vranec

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  1. Ivan Potočňák
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  2. Peter Vranec
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Correspondence to Ivan Potočňák.

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Potočňák, I., Vranec, P. Low-dimensional compounds containing bioactive ligands. I: Crystal structure, spectroscopic, and thermal properties of the first row transition metal coordination compounds with clioquinol. Monatsh Chem 143, 217–226 (2012). https://doi.org/10.1007/s00706-011-0678-0

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  • DOI: https://doi.org/10.1007/s00706-011-0678-0

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