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Microwave-assisted synthesis of symmetrical and unsymmetrical N,N′-disubstituted thioureas and ureas over MgO in dry media

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Abstract

Under mild microwave irradiation conditions a variety of symmetrical and unsymmetrical N,N′-disubstituted thioureas and ureas were prepared via the reaction of N-monosubstituted hydroxylamines with isocyanate and isothiocyanate derivatives over MgO under solvent-free conditions. This new method afforded satisfactory results with good yields, short reaction time, and simplicity in the experimental procedure.

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Acknowledgments

The partial financial assistance from the Research Vice Chancellor of Azarbaijan University of Tarbiat Moallem is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences, Azarbaijan University of Tarbiat Moallem, Tabriz, Iran

    Hassan Valizadeh & Leila Dinparast

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  1. Hassan Valizadeh
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  2. Leila Dinparast
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Correspondence to Hassan Valizadeh.

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Valizadeh, H., Dinparast, L. Microwave-assisted synthesis of symmetrical and unsymmetrical N,N′-disubstituted thioureas and ureas over MgO in dry media. Monatsh Chem 143, 251–254 (2012). https://doi.org/10.1007/s00706-011-0583-6

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  • DOI: https://doi.org/10.1007/s00706-011-0583-6

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