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Synthesis and antimicrobial activity of tetrazolo[1,5-a]quinoline-4-carbonitrile derivatives

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An Erratum to this article was published on 01 July 2010

Abstract

A series of new tetrazolo[1,5-a]quinoline-4-carbonitrile derivatives were synthesized for the first time via tetrazolo[1,5-a]quinoline derivatives. Elemental analysis, IR, 1H NMR, 13C NMR, and mass spectral data were used to elucidate the structures of all newly synthesized compounds. In vitro antimicrobial activities of synthesized compounds were investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli, and two fungi, Candida albicans and Aspergillus niger, in comparison with standard drugs. Some of the tested compounds showed significant antimicrobial activity.

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Acknowledgments

The authors would like to thank the Head of the Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad for constant encouragement and providing necessary facilities. AmHK also wishes to express his gratitude to the University Grant Commission, New Delhi for providing the financial support as a Rajiv Gandhi National Fellowship to carry out the present work.

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Authors and Affiliations

  1. Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, 431 004, India

    Amol H. Kategaonkar, Vilas B. Labade, Pravin V. Shinde, Bapurao B. Shingate & Murlidhar S. Shingare

  2. Pharmacology Laboratory, Maharashtra Institute of Pharmacy, Pune, Maharashtra, 411 038, India

    Atul H. Kategaonkar

Authors
  1. Amol H. Kategaonkar
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  2. Vilas B. Labade
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  3. Pravin V. Shinde
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  4. Atul H. Kategaonkar
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  5. Bapurao B. Shingate
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  6. Murlidhar S. Shingare
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Corresponding author

Correspondence to Murlidhar S. Shingare.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s00706-010-0356-7

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Kategaonkar, A.H., Labade, V.B., Shinde, P.V. et al. Synthesis and antimicrobial activity of tetrazolo[1,5-a]quinoline-4-carbonitrile derivatives. Monatsh Chem 141, 787–791 (2010). https://doi.org/10.1007/s00706-010-0324-2

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  • DOI: https://doi.org/10.1007/s00706-010-0324-2

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