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Regioselective synthesis of 4-aryl-3,4-dihydro-1,3,5-triazino[2,1-a]isoindol-2-ones

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Abstract

The condensation of binucleophilic 3-amino-1-arylimino-1H-isoindoles with bifunctional 1-chloro-benzylisocyanates occurs regioselectively resulting in 3,4-dihydro-1,3,5-triazino[2,1-a]isoindol-2-one derivatives. The structures of the synthesized compounds were unambiguously established by NOE experiments.

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Authors and Affiliations

  1. Chemistry Department, Kyiv National Taras Shevchenko University, Kyiv, Ukraine

    Angelina V. Biitseva & Olha V. Hordiyenko

  2. Institute of Organic Chemistry, National Academy of Sciences, Kyiv, Ukraine

    Volodymyr A. Sukach & Myhailo V. Vovk

  3. STC “Institute for Single Crystals”, National Academy of Sciences, Kharkiv, Ukraine

    Konstantin A. Pichugin, Irina S. Konovalova & Oleg V. Shishkin

Authors
  1. Angelina V. Biitseva
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  2. Olha V. Hordiyenko
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  3. Volodymyr A. Sukach
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  4. Myhailo V. Vovk
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  5. Konstantin A. Pichugin
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  6. Irina S. Konovalova
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  7. Oleg V. Shishkin
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Corresponding author

Correspondence to Olha V. Hordiyenko.

Additional information

Correspondence: Olha V. Hordiyenko, Chemistry Department, Kyiv National Taras Shevchenko University, 01033 Kyiv, Ukraine.

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Biitseva, A., Hordiyenko, O., Sukach, V. et al. Regioselective synthesis of 4-aryl-3,4-dihydro-1,3,5-triazino[2,1-a]isoindol-2-ones. Monatsh Chem 139, 939–943 (2008). https://doi.org/10.1007/s00706-008-0860-1

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  • DOI: https://doi.org/10.1007/s00706-008-0860-1

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