Skip to main content
SpringerLink
Log in

Practical and general method for the direct synthesis of alkyl fluorides from alcohols under mild conditions: a reinvestigation

  • Original Paper
  • Published:
Monatshefte für Chemie - Chemical Monthly Aims and scope Submit manuscript

Abstract

In contrast to the results presented in a previous report, the direct conversion of alcohols to alkyl fluorides with triphenylphosphine and potassium fluoride in CCl4/DMF under mild conditions failed.

Graphical Abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme 1
Scheme 2

Similar content being viewed by others

References

  1. Purser S, Moore PR, Swallow S, Gouverneur V (2008) Chem Soc Rev 37:320

    Article  CAS  Google Scholar 

  2. Bandgar BP, Kamble VT, Biradar AV (2005) Monatsh Chem 136:1579

    Article  CAS  Google Scholar 

  3. Manna S, Falck JR, Mioskowski C (1985) Synth Commun 15:663

    Article  CAS  Google Scholar 

  4. Maeda H, Koide T, Matsumoto S, Ohmori H (1996) Chem Pharm Bull 44:1480

    CAS  Google Scholar 

  5. Kappe CO (2004) Angew Chem Int Edit 43:6250

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This work was supported by a grant from the “Jubiläumsfonds der österreichischen Nationalbank,” Project No. 11979, and the “Mitteln des vom Land Tirol eingerichteten Wissenschaftsfonds,” Project No. UNI-0404/275.

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, Innsbruck Medical University, 6020, Innsbruck, Austria

    Marco Rupprich & Clemens Decristoforo

  2. Department of Pharmacy, University of Innsbruck, 6020, Innsbruck, Austria

    Marco Rupprich & Barbara Matuszczak

Authors
  1. Marco Rupprich
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Clemens Decristoforo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Barbara Matuszczak
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Marco Rupprich.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rupprich, M., Decristoforo, C. & Matuszczak, B. Practical and general method for the direct synthesis of alkyl fluorides from alcohols under mild conditions: a reinvestigation. Monatsh Chem 140, 405–407 (2009). https://doi.org/10.1007/s00706-008-0041-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00706-008-0041-2

Keywords

Search

Navigation