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Amino Acid Derivatives, VII [1]: Synthesis and Antiviral Evaluation of α-Amino Acid Esters Bearing an Indazole Side Chain

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Summary.

A series of peptide and dipeptide derivatives conjugated with an indazole residue were synthesized. The new compounds were evaluated in vitro for cytotoxicity against Hepatitis-A virus (HAV-27), Herpes Simplex virus-1 (HSV-1), and Hepatitis-B virus (HBV) and showed moderate to high activity.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt

    Adel A.-H. Abdel-Rahman

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  1. Adel A.-H. Abdel-Rahman
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Correspondence to Adel A.-H. Abdel-Rahman.

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Abdel-Rahman, AH. Amino Acid Derivatives, VII [1]: Synthesis and Antiviral Evaluation of α-Amino Acid Esters Bearing an Indazole Side Chain. Monatsh Chem 139, 289–297 (2008). https://doi.org/10.1007/s00706-007-0770-7

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  • DOI: https://doi.org/10.1007/s00706-007-0770-7

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