Summary.
The multicomponent Strecker reaction using trimethylsilyl cyanide was performed at room temperature and α-aminonitriles were prepared in excellent yields in the presence of a catalytic amount of H2SO4 adsorbed on silica gel.
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Oskooie, H., Heravi, M., Sadnia, A. et al. H2SO4/Silicagel: Highly Efficient Catalyst for the Synthesis of α-Aminonitriles Using Trimethysilyl Cyanide. Monatsh. Chem. 139, 27–29 (2008). https://doi.org/10.1007/s00706-007-0740-0
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DOI: https://doi.org/10.1007/s00706-007-0740-0