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Ionic Liquid Promoted Eco-friendly and Efficient Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

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Summary.

2,3-Dihydroquinazolin-4(1H)-ones were efficiently synthesised by the reaction of isatoic anhydride, a primary amine or ammonium acetate, and different aromatic aldehydes in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) without using any acidic catalyst. Also a bis-derivative of the title compound as a polyheterocyclic system was synthesised successfully in high yield.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Shahid Beheshti University, Evin, Tehran, Iran

    Minoo Dabiri & Mostafa Baghbanzadeh

  2. Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, Iran

    Peyman Salehi

Authors
  1. Minoo Dabiri
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  2. Peyman Salehi
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  3. Mostafa Baghbanzadeh
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Correspondence to Minoo Dabiri or Peyman Salehi.

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Dabiri, M., Salehi, P. & Baghbanzadeh, M. Ionic Liquid Promoted Eco-friendly and Efficient Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones. Monatsh. Chem. 138, 1191–1194 (2007). https://doi.org/10.1007/s00706-007-0635-0

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  • DOI: https://doi.org/10.1007/s00706-007-0635-0

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