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Synthesis of a New Furanoid Glycal Auxiliary

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Summary.

A route is investigated for the synthesis of 3-O-allyl-1,4-anhydro-5-O-tert-butyldiphenylsilyl-2-deoxy-D-erythro-pent-1-enitol. The highest overall yield was obtained when 5′-O-(tert-butyldiphenylsilyl)thymidine was converted to the corresponding furanoid glycal and subsequently 3-O-allylated.

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Authors and Affiliations

  1. Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, DK-5230, Odense M, Denmark

    Youssef L. Aly & Erik B. Pedersen

Authors
  1. Youssef L. Aly
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  2. Erik B. Pedersen
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Corresponding author

Correspondence to Erik B. Pedersen.

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On leave from Chemistry Department, Faculty of Education Kafr El-Sheikh branch Tanta University, Kafr El-Sheikh, Egypt

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Aly, Y., Pedersen, E. Synthesis of a New Furanoid Glycal Auxiliary. Monatsh. Chem. 136, 1641–1644 (2005). https://doi.org/10.1007/s00706-005-0342-7

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  • DOI: https://doi.org/10.1007/s00706-005-0342-7

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