Summary.
5-Isopropylidene-2,2-dimethyl-1,3-dioxane-4,6-dione (the condensation product of Meldrum’s acid and acetone) reacts smoothly with tert-butyl isocyanide in the presence of primary or secondary amines to produce N-tert-butyl-2,2-dimethylbutyramide derivatives and/or 1-tert-butyl-4,4-dimethyl-2,5-dioxopyrrolidine-3-carboxamides in good yields.
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Yavari, I., Habibi, A., Hosseini-Tabatabaei, M. et al. Reaction Between 5-Isopropylidene-2,2-dimethyl-1,3-dioxane-4,6-dione and tert-Butyl Isocyanide in the Presence of Primary or Secondary Amines. Monatshefte für Chemie 134, 1651–1658 (2003). https://doi.org/10.1007/s00706-003-0619-7
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DOI: https://doi.org/10.1007/s00706-003-0619-7