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Synthesis of 6-Heterocyclically Appended Tri-O-methyl Protected 6-Desmethyl Emodin Derivatives

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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary.

A convenient synthesis of several 6-heterocyclically appended tri-O-methyl 6-desmethyl emodin derivatives including the tetrazolyl, oxazolyl, oxazolinyl, benzimidazolyl, benzoxazolyl, and benzothiazolyl derivatives of potential biological and medicinal interest was achieved starting from the tri-O-methyl protected emodin aldehyde or nitrile. In addition, these derivatives could serve as synthons for heterocyclic hypericin derivatives.

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Correspondence to Heinz Falk.

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Salama, T., Lackner, B. & Falk, H. Synthesis of 6-Heterocyclically Appended Tri-O-methyl Protected 6-Desmethyl Emodin Derivatives. Monatshefte für Chemie 135, 735–742 (2004). https://doi.org/10.1007/s00706-003-0151-9

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  • DOI: https://doi.org/10.1007/s00706-003-0151-9

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