Summary.
A convenient synthesis of 3-substituted [1,2,4]triazolo[4,3-e]caffeines by oxidative cyclization of 8-arylmethylenehydrazinocaffeines with bromine in acetic acid in presence of sodium acetate is described.
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Received May 6, 2002; accepted June 13, 2002
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Mosselhi, M., Tawfik, N. & Shawali, A. New [e]-Fused Caffeines: A Simple Synthesis of 3-Substituted [1,2,4]Triazolo[4,3-e]purines. Monatshefte für Chemie 134, 565–571 (2003). https://doi.org/10.1007/s00706-002-0514-7
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DOI: https://doi.org/10.1007/s00706-002-0514-7