Summary.
2-Amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene with ethyl β-amino-α-cyano-γ-ethoxycarbonylcrotenoate yields the corresponding amide derivative. That compound reacts with benzenediazonium chloride to give the phenyl hydrazone derivative. This type of compounds was cyclized to give pyridazine and pyridine derivatives, respectively. Chemical reactivities of the latter were studied to give fused heterocyclic compounds with antimicrobial activities.
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Received February 8, 2002; accepted (revised) March 28, 2002
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Mohareb, R., Al-Omran, F. & Ho, J. Reaction of 3-Cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene with Enaminonitriles. Monatshefte für Chemie 133, 1443–1452 (2002). https://doi.org/10.1007/s00706-002-0494-7
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DOI: https://doi.org/10.1007/s00706-002-0494-7