Summary.
Reaction of 6-Amino-2-thiouracil with hydrazonoyl halides yielded regioselectively 7-amino-1,3-disubstituted-1,2,4-triazolo[4,3-a]pyrimidine derivatives. Upon treatment with methyl (Z)-2-benzoylamino-3-dimethylaminopropenoate, the corresponding methyl (Z)-2-benzoylamino-3-([1,2, 4]triazolo[4,3-a]pyrimidin-7-yl)-amino propenoates were obtained which cyclized in the presence of sodium ethoxide to afford novel derivatives of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-(1H,8H)-diones.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
E-mail: mosselhi@chem-sci.cairo.eun.eg
Received February 8, 2002; accepted (revised) March 18, 2002
Rights and permissions
About this article
Cite this article
Mosselhi, M. A Convenient Synthesis of NovelDerivatives of Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-dione. Monatshefte für Chemie 133, 1297–1304 (2002). https://doi.org/10.1007/s00706-002-0469-8
Issue Date:
DOI: https://doi.org/10.1007/s00706-002-0469-8