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Archives of Virology

, Volume 145, Issue 8, pp 1509–1520 | Cite as

Pityriasis rosea – a virus-induced skin disease? An update

  • W. Kempf
  • G. Burg
Brief Review

Summary.

 Pityriasis rosea (PR) is an acute, inflammatory skin disease of unknown cause. Clinical and experimental findings indicate an infectious etiology of PR. Various infectious agents including viruses have been proposed as causative agents and their presence in PR samples has been extensively investigated. Recently, human herpesvirus 7 was linked to PR, but contradictory findings have been reported by various investigators. Here, we describe the features of PR that suggest an infectious cause and review the data from viral studies in PR reported in the literature. In addition, we present a pathogenetic model of PR which may be helpful in planning and evaluating studies for the search of a putative PR-associated virus. Based on the current state of knowledge, none of the known viruses could, so far, be conclusively associated with PR.

Keywords

Causative Agent Experimental Finding Skin Disease Infectious Agent Contradictory Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 2000

Authors and Affiliations

  • W. Kempf
    • 1
  • G. Burg
    • 1
  1. 1.Department of Dermatology, University Hospital, Zurich, SwitzerlandCH

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