Summary
Autographa californica M nucleopolyhedrovirus (AcMNPV) is a large ds DNA virus restricted to larval lepidopteran insect hosts. Using field inversion gel electrophoresis and digestion with a restriction enzyme which cuts the AcMNPV genome once, we detected multiple unit-length genome fragments from replicating viral DNA. Our data suggest that AcMNPV replicates in a head-to-tail manner via rolling circle replication.
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Received March 26, 1997 Accepted May 2, 1997
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Oppenheimer, D.I., Volkman, L.E. Evidence for rolling circle replication of Autographa californica M nucleopolyhedrovirus genomic DNA. Arch. Virol. 142, 2107–2113 (1997). https://doi.org/10.1007/s007050050229
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DOI: https://doi.org/10.1007/s007050050229