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First detection of Psittacid alphaherpesvirus 5 and coinfection with beak and feather disease virus in naturally infected captive ringneck parakeets (Psittacula krameri) in Brazil

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Abstract

This study describes a case report in captive rose-ringed parakeets (Psittacula krameri) that developed clinical signs and eventually died after introducing new birds without quarantine. Bronchopneumonia and airsacculitis with syncytial cells associated with intranuclear inclusion bodies were found. Herpesvirus was detected in lungs and liver by PCR, and a nearly complete genome sequence of a Psittacid alphaherpesvirus 5 was obtained from the lung of a bird. Metagenomic analysis also identified beak and feather disease virus in the same samples. The study also highlights the importance of quarantine for avoiding the introduction of new diseases in captive aviaries.

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References

  1. Bottinelli M, Fortin A, Zanardello C, Budai J, Gobbo F, Antonazzo G, Leone S, Merenda M, Terregino C, Catania S (2022) Herpetic pneumonia in indian ringneck parrots (Psittacula krameri): first report of novel Psittacid Alphaherpesvirus-5 infection in Europe. Animals (Basel). https://doi.org/10.3390/ani12020188

    Article  Google Scholar 

  2. Gabor M, Gabor LJ, Peacock L, Srivastava M, Rosenwax A, Phalen D (2013) Psittacid herpesvirus 3 infection in the eclectus parrot (Eclectus roratus) in Australia. Vet Pathol 50:1053–1057. https://doi.org/10.1177/0300985813490753

    Article  CAS  PubMed  Google Scholar 

  3. Gatherer D, Depledge DP, Hartley CA, Szpara ML, Vaz PK, Benko M, Brandt CR, Bryant NA, Dastjerdi A, Doszpoly A, Gompels UA, Inoue N, Jarosinski KW, Kaul R, Lacoste V, Norberg P, Origgi FC, Orton RJ, Pellett PE, Schmid DS, Spatz SJ, Stewart JP, Trimpert J, Waltzek TB, Davison AJ (2021) ICTV virus taxonomy profile: herpesviridae 2021. J Gen Virol. https://doi.org/10.1099/jgv.0.001673

    Article  PubMed  PubMed Central  Google Scholar 

  4. Harkins GW, Martin DP, Christoffels A, Varsani A (2014) Towards inferring the global movement of beak and feather disease virus. Virology 450–451:24–33. https://doi.org/10.1016/j.virol.2013.11.033

    Article  CAS  PubMed  Google Scholar 

  5. Helfer DH, Schmitz JA, Seefeldt SL, Lowenstine L (1980) A new viral respiratory infection in parakeets. Avian Dis 24:781–783

    Article  CAS  Google Scholar 

  6. ICTV (2020) Virus taxonomy: 2020 release. Elsevier Academic Press, San Diego

    Google Scholar 

  7. Iñigo-Ellias EE (2007) Parrots of the world: an identification guide. Auk 124:1099–1101. https://doi.org/10.1642/0004-8038(2007)124[1099:POTWAI]2.0.CO;2

    Article  Google Scholar 

  8. Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol 33:1870–1874. https://doi.org/10.1093/molbev/msw054

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Lazic T, Ackermann MR, Drahos JM, Stasko J, Haynes JS (2008) Respiratory herpesvirus infection in two Indian Ringneck parakeets. J Vet Diagn Invest 20:235–238. https://doi.org/10.1177/104063870802000217

    Article  PubMed  Google Scholar 

  10. Panigrahy B, Grumbles LC (1984) Pacheco’s disease in psittacine birds. Avian Dis 28:808–812

    Article  CAS  Google Scholar 

  11. Prophet EB, Mills B, Arrington JB, Sobin LH (1992) Laboratory methods in histotechnology. American Registry of Pathology, Washington, D.C.

    Google Scholar 

  12. Rizotto LS, Scagion GP, Cardoso TC, Simão RM, Caserta LC, Benassi JC, Keid LB, Oliveira TMdS, Soares RM, Arns CW, Van Borm S, Ferreira HL (2017) Complete genome sequence of an avian metapneumovirus subtype a strain, isolated from chicken (Gallus gallus) in Brazil. Genome Announc 5

  13. Shivaprasad HL, Phalen DN (2012) A novel herpesvirus associated with respiratory disease in Bourke’s parrots (Neopsephotus bourkii). Avian Pathol 41:531–539. https://doi.org/10.1080/03079457.2012.732692

    Article  CAS  PubMed  Google Scholar 

  14. Sutherland M, Sarker S, Raidal SR (2019) Molecular and microscopic characterisation of a novel pathogenic herpesvirus from Indian ringneck parrots (Psittacula krameri). Vet Microbiol 239:108428. https://doi.org/10.1016/j.vetmic.2019.108428

    Article  CAS  PubMed  Google Scholar 

  15. Sutherland M, Sarker S, Vaz PK, Legione AR, Devlin JM, Macwhirter PL, Whiteley PL, Raidal SR (2019) Disease surveillance in wild Victorian cacatuids reveals co-infection with multiple agents and detection of novel avian viruses. Vet Microbiol 235:257–264. https://doi.org/10.1016/j.vetmic.2019.07.012

    Article  PubMed  Google Scholar 

  16. Tamura K, Nei M, Kumar S (2004) Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci USA 101:11030–11035. https://doi.org/10.1073/pnas.0404206101

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673–4680

    Article  CAS  Google Scholar 

  18. Tsai SS, Hirai K, takura C, (1993) Herpesvirus infection in psittacine birds in Japan. Avian Pathol 22:141–156

    Article  CAS  Google Scholar 

  19. VanDevanter DR, Warrener P, Bennett L, Schultz ER, Coulter S, Garber RL, Rose TM (1996) Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol 34:1666–1671. https://doi.org/10.1128/JCM.34.7.1666-1671.1996

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Woods LW, Latimer KS (2013) Circovirus infections of avian species. In: Swayne DE, Boulianne M, Logue CM, McDougald LR, Nair V, Suarez DL (eds) Diseases of poultry. Wiley, Oxford, pp 264–288

    Google Scholar 

  21. Yang N, McLelland J, McLelland DJ, Clarke J, Woolford L, Eden P, Phalen DN (2019) Psittacid Adenovirus-2 infection in the critically endangered orange-bellied parrot (Neophema chrysogastor): a key threatening process or an example of a host-adapted virus? PLoS ONE 14:e0208674. https://doi.org/10.1371/journal.pone.0208674

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

We are grateful to Julia C. Benassi for her technical assistance. HLF, FRS, and LMB are recipients of CNPq scholarships. LMNS and MVSM are recipients of CAPES scholarships.

Funding

This work was funded by FAPESP (2019/13198-0), by the Ministry of Science, Technology, and Innovation (MCTI-Brazil), and by the National Council for Scientific and Technological Development (RedeVirus-MCTI/CNPq: 403761/2020-4). HLF, FRS, and LMB are recipients of CNPq scholarships. LMNS and MVSM are recipients of CAPES scholarships. We also thank the National Network for Virus Surveillance in Wild Animals (PREVIR-MCTI Network), Conselho Nacional de Desenvolvimento Científico e Tecnológico, grant no: 302668/2018-7, Conselho Nacional de Desenvolvimento Científico e Tecnológico, grant no: 316333/2021-2.

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Author notes

  1. Roselene Ecco and Laura Morais Nascimento Silva contributed equally to this work.

Authors and Affiliations

  1. Setor de Patologia, Departamento de Clínica e Cirurgia, Escola de Veterinária, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, Belo Horizonte, MG, 31270-901, Brazil

    Roselene Ecco, Maira dos Santos Carneiro Lacerda, Letícia Batelli de Oliveira, Willian Henrique de Magalhães Santos & Luís Henrique Gouvêa Saraiva

  2. Programa de pós-graduação em epidemiologia experimental aplicada às Zoonoses, FMVZ-USP, Av. Prof. Dr. Orlando M. de Paiva, 87, São Paulo, SP, 05508-270, Brazil

    Laura Morais Nascimento Silva, Maria Vitória dos Santos de Moraes, Laís Santos Rizotto & Helena Lage Ferreira

  3. Departamento de Medicina Veterinária, FZEA-USP, Rua Duque de Caxias Norte, 225, Pirassununga, SP, 13635900, Brazil

    Larissa Mayumi Bueno & Helena Lage Ferreira

  4. Instituto de Ciências Biomédicas, Universidade de São Paulo, Av. Prof. Lineu Prestes 1374, São Paulo, SP, 05508-000, Brazil

    Erick G. Dorlass & Edison Luiz Durigon

  5. Laboratório de Microbiologia Molecular, Universidade Feevale, Rodovia ERS-239, 2755, Prédio Vermelho, Piso 1, Sala 103, Vila Nova, Novo Hamburgo, RS, 93525-075, Brazil

    Fernando Rosado Spilki

Authors
  1. Roselene Ecco
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  2. Laura Morais Nascimento Silva
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  4. Maria Vitória dos Santos de Moraes
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  11. Edison Luiz Durigon
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  12. Fernando Rosado Spilki
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  13. Helena Lage Ferreira
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Contributions

All authors contributed to the study conception and performed the research. Data collection and analysis were performed by HLF, LMNS, MVSM, FRS, RE, EGD. The first draft of the manuscript was written by RE, HLF, LMNS, and MVSM, and all authors commented on previous versions of the manuscript. Funding was acquired by HLF and ELD. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Helena Lage Ferreira.

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Conflict of interest

All authors declare that they have no relevant financial or non-financial interests to disclose.

Ethical approval

All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. This work was performed following the animal protection guidelines and legal approval (Ethics Committee on Animal Use, University of São Paulo – CEUA-FZEA 1355190521). This article does not contain any studies with human participants performed by any of the authors.

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GenBank accession numbers: The nucleotide sequence data reported here are available in the GenBank databases under the accession numbers OM144906 (partial DNA polymerase sequence of PsAHV-5), OK670608 (nearly complete genome sequence of PsAHV-5), and OL362209 (complete genome sequence of BFDV).

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Ecco, R., Silva, L.M.N., dos Santos Carneiro Lacerda, M. et al. First detection of Psittacid alphaherpesvirus 5 and coinfection with beak and feather disease virus in naturally infected captive ringneck parakeets (Psittacula krameri) in Brazil. Arch Virol 167, 2319–2324 (2022). https://doi.org/10.1007/s00705-022-05566-9

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