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The first feline immunodeficiency virus from Siberian tigers (Panthera tigris altaica) in northeastern China

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Abstract

Feline immunodeficiency virus (FIV) naturally infects more than 20 kinds of felines and poses a serious threat to their health, but there has been little research on FIV in tigers. In this study, 320 captive Siberian tigers (225 from Harbin, 55 from Hailin, and 40 from Shenyang) were tested for FIV by nested PCR, and three Siberian tigers from Hailin were FIV positive (5.45%). From these three animals, FIV gene fragments, gag-p26 (444 nt) from samples HD094 and HD1786 and pol-RT (576 nt) and pol-RNase (730 nt) from sample HD631, were sequenced and found to share more than 99% sequence identity with FIV subtype A from domestic cats. This is the first time FIV has been detected in Siberian tigers in China.

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Acknowledgments

We thank the National Forestry and Grassland Administration of China for the Surveillance of Wildlife Diseases Project for financial support. We also thank the staff of the Siberian Tiger Park for their participation in sample collection.

Funding

This research was funded by Surveillance of Wildlife Diseases from the National Forestry and Grassland Administration of China.

Author information

Author notes

  1. Enqi Liu and Liying Ma should be considered joint first author.

Authors and Affiliations

  1. College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, Heilongjiang, People’s Republic of China

    Enqi Liu, Liying Ma, Shuping Huang, Dan You, Lijun Guo, Xiang Li, Hongliang Chai & Yajun Wang

  2. Siberian Tiger Park, Harbin, Heilongjiang, People’s Republic of China

    Haitao Xu & Dan Liu

Authors
  1. Enqi Liu
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Contributions

Conceptualization: YW. Methodology: YW, EL, LM. Formal analysis and investigation: EL, LM, SH. Writing–original draft preparation: EL. Writing–review and editing: YW, EL, XL. Funding acquisition: YW, HC. Resources, DY, LG, HX, DL. Supervision: YW, HC.

Corresponding author

Correspondence to Yajun Wang.

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The authors declare that they have no conflict of interest.

Ethics statement

The authors confirm that the ethical policies of the journal, as noted on the journal’s author guidelines page, have been adhered to and that was received from the Laboratory Animal Management and Ethics Committee of Northeast Forestry University approval.

Data availability

Nucleotide sequence data reported are available in the GenBank databases under the accession numbers MW809410 to MW809412 and MZ189264.

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Handling Editor: Ana Cristina Bratanich.

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Liu, E., Ma, L., Huang, S. et al. The first feline immunodeficiency virus from Siberian tigers (Panthera tigris altaica) in northeastern China. Arch Virol 167, 545–551 (2022). https://doi.org/10.1007/s00705-022-05370-5

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