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Pigeon adenovirus and pigeon torque teno virus associated with acute multifocal hepatic necrosis in pigeons in Queensland, Australia

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Abstract

In 2018, an outbreak resulting in deaths of 28 breeding pigeons was reported north of Brisbane, Australia. The affected birds had runny nasal discharge and poor body condition. Two birds were submitted to Biosecurity Sciences Laboratory, Brisbane, for investigation. A range of diagnostic tests excluded a number of known pathogens, and no virus was isolated in cell culture. Histopathological examination revealed severe acute multifocal necrosis in the liver with eosinophilic intranuclear inclusions in hepatocytes and Kupffer cells. High-throughput sequencing (HTS) revealed full-length sequences for pigeon adenovirus 1 (PiAd-A) and pigeon torque teno virus (PTTV). This report indicates concomitant PiAd-1and PTTV infections in Australian pigeons.

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Acknowledgements

We thank Dr. Gavin Wilkie at Illumina for his sequencing expertise and assistance. We thank Darren Underwood, Les Barker, Cath Covacin, and Wafa Shinwari for the laboratory data. We also thank Shirley Turner and Louise Jackson for useful comments in preparation of the manuscript. This work was funded by Biosecurity Queensland, Queensland Department of Agriculture and Fisheries.

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Authors and Affiliations

  1. Biosecurity Sciences Laboratory, Biosecurity Queensland, Department of Agriculture and Fisheries, Queensland Government, Health and Food Sciences Precinct, 39, Coopers Plains, QLD, 4108, Australia

    Kalpana Agnihotri, Craig Smith, Jane Oakey & Greg Storie

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  1. Kalpana Agnihotri
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  2. Craig Smith
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  3. Jane Oakey
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  4. Greg Storie
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Correspondence to Kalpana Agnihotri.

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Agnihotri, K., Smith, C., Oakey, J. et al. Pigeon adenovirus and pigeon torque teno virus associated with acute multifocal hepatic necrosis in pigeons in Queensland, Australia. Arch Virol 166, 1469–1475 (2021). https://doi.org/10.1007/s00705-021-05033-x

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  • DOI: https://doi.org/10.1007/s00705-021-05033-x

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