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Genetic diversity of porcine circovirus 3 strains and the first detection of two different PCV3 strains coinfecting the same host in Minas Gerais, Brazil

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Abstract

Porcine circovirus 3 (PCV3) is a recently emerged circovirus discovered in 2016 that has drawn the attention of the swine industry worldwide. In this study, we evaluated the genetic diversity of PCV3 strains on pig farms. A total of 261 samples from sows, weaning pigs, growing pigs, and stillborn/mummified fetuses were analyzed by quantitative real-time PCR. The results revealed that at least two main lineages of PCV3 are circulating in Brazil. For the first time, it was possible to detect the presence of two different PCV3 strains in the same host.

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Acknowledgements

This research was supported by the Brazilian Government Agencies CAPES, CNPq, and FAPEMIG.

Funding

This research received funding from CNPq.

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Authors and Affiliations

  1. Veterinary Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, 36570-900, Brazil

    Viviane Sisdelli Assao, Marcus Rebouças Santos, Nívia Carolina Lopes Rosado & Abelardo Silva-Júnior

  2. Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, 36570-900, Brazil

    Gustavo Costa Bressan & Juliana Lopes Rangel Fietto

  3. College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA

    Yung-Fu Chang

  4. Núcleo de Análises e Biomoléculas, Universidade Federal de Viçosa, Viçosa, Minas Gerais, 36570-900, Brazil

    Pedro Marcus Pereira Vidigal

Authors
  1. Viviane Sisdelli Assao
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  2. Marcus Rebouças Santos
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  3. Nívia Carolina Lopes Rosado
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  4. Gustavo Costa Bressan
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  5. Juliana Lopes Rangel Fietto
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  6. Yung-Fu Chang
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  7. Pedro Marcus Pereira Vidigal
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  8. Abelardo Silva-Júnior
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Contributions

The study was conceived, designed, and critically revised by VSA, MRS, NCLR, GCB, JLRF, YFC, PMPV, and ASJ. Data analysis and drafting of the manuscript were carried out by VSA, MRS, PMPV, and ASJ. All authors have read and agreed to the published version of the manuscript.

Corresponding authors

Correspondence to Pedro Marcus Pereira Vidigal or Abelardo Silva-Júnior.

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Conflict of interest

The authors have declared no conflicts of interest.

Ethical approval

The authors confirm that the sample collection in this study was carried out in strict accordance with the Animal Ethics Committee of the Federal University of Viçosa.

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The data that support the findings of this study are available in the supplementary materials of this article.

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Handling Editor: Sheela Ramamoorthy.

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Assao, V.S., Santos, M.R., Rosado, N.C.L. et al. Genetic diversity of porcine circovirus 3 strains and the first detection of two different PCV3 strains coinfecting the same host in Minas Gerais, Brazil. Arch Virol 166, 1463–1468 (2021). https://doi.org/10.1007/s00705-021-05032-y

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  • DOI: https://doi.org/10.1007/s00705-021-05032-y

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