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Complete nucleotide sequence of a new carlavirus infecting Aconitum carmichaelii in China

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Abstract

A novel virus was identified in aconite (Aconitum carmichaelii Debx.) in China by high-throughput sequencing (HTS) and tentatively named "aconite virus A" (AcVA). The genomic RNA of AcVA consists of 8,844 nucleotides, excluding the poly(A) at the 3′ end. Analysis of the genomic organization of AcVA indicated that it possesses a genomic structure that is typical of carlaviruses and contains six putative open reading frames (ORFs). Pairwise analysis revealed that the replicase and coat protein of AcVA share the highest amino acid sequence identity (43.78% and 57.01%) with those of coleus vein necrosis virus (CVNV) and butterbur mosaic virus (ButMV), respectively. Based on the current classification criteria for carlaviruses, AcVA should be considered a distinct member of the genus Carlavirus.

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Funding

This work was supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (grant number 2016-I2M-3-017); Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources (2060302).

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Authors and Affiliations

  1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 151 Malianwa North Road, Beijing, 100193, China

    Rong Wang, Bingwei Chen, Yong Li & Wanlong Ding

  2. National Citrus Engineering Research Center, Citrus Research Institute, Southwest University, Chongqing, 400712, China

    Mengji Cao

  3. Academy of Agricultural Sciences, Southwest University, Chongqing, 400715, China

    Mengji Cao

Authors
  1. Rong Wang
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  2. Bingwei Chen
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  3. Yong Li
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  4. Mengji Cao
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  5. Wanlong Ding
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Correspondence to Wanlong Ding.

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The authors declare that they have no conflict of interest.

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This study did not include experiments with human participants or animals performed by any of the authors.

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Wang, R., Chen, B., Li, Y. et al. Complete nucleotide sequence of a new carlavirus infecting Aconitum carmichaelii in China. Arch Virol 166, 1513–1515 (2021). https://doi.org/10.1007/s00705-021-05028-8

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  • DOI: https://doi.org/10.1007/s00705-021-05028-8

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