Abstract
In the study, three Bacillus cereus-specific phages, named DK1, DK2 and DK3, belonging to the family Podoviridae, were isolated from Pearl River water and sludge in Guangzhou, China. The genomes of DK1, DK2 and DK3 were 27,180 bp, 26,357 bp, and 26,865 bp in length and contained 49, 45 and 46 open reading frames, respectively. Among the three phages, DK2 shared the highest genome sequence similarity (96% identity) with DK3. Genes encoding rRNA, tRNA, virulence factors and antibiotic resistance were absent in these phage genomes. In addition, comparative genomic and phylogenetic analysis revealed that they were novel phages of B. cereus. Each genome encoded a putative endolysin that might be of value for the control of the foodborne pathogen B. cereus.
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17 January 2025
A Correction to this paper has been published: https://doi.org/10.1007/s00705-024-06216-y
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Funding
This study was funded by the National Key R&D Program of China (grant number 2018YFC1602500), the National Natural Science Foundation of China (grant number 31730070), the Science and Technology Program of Guangzhou, China (grant number 201604016068), the State Key Laboratory of Applied Microbiology Southern China (grant numbers SKLAM004-2016 and SKLAM006-2016), GDAS’ Special Project of Science and Technology Development (grant number 2017GDASCX-0201), the Fundamental Research Funds for the Central Universities, and the 111 Project. YD received a 1000-Youth Elite Program award.
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Kong, L., Ding, Y., Wu, Q. et al. Genome sequencing and characterization of three Bacillus cereus-specific phages, DK1, DK2, and DK3. Arch Virol 164, 1927–1929 (2019). https://doi.org/10.1007/s00705-019-04258-1
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DOI: https://doi.org/10.1007/s00705-019-04258-1