Coinfection of a lingual lesion with bovine papular stomatitis virus and bovine papillomavirus
To date, there have been no reports of coinfection with bovine papular stomatitis virus (BPSV) and bovine papillomavirus (BPV) in the same lesion. In the present study, one lingual papilloma-like sample was collected at an abattoir from the tongue of a 31-month-old Japanese black cow. Coinfection with BPSV and BPV was confirmed by histopathology, immunohistochemistry, PCR and RT-PCR. The evidence for coinfection with BPSV and BPV in the same lesion and an association of BPV with lingual papillomatosis will contribute to future epidemiological studies of these two viruses.
We are grateful to the Tsuno Meat Inspection Center of Miyazaki Prefecture for providing sample MY-51, and Drs. Yasuo Inoshima and Tomoyuki Shibahara for providing BPSV antiserum.
This study was supported by the Shandong Province Modern Agricultural Industry Technology System (SDAIT-09-05) and the Japan Society for the Promotion of Science (KAKENHI 24-1466).
Compliance with ethical standards
Conflict of interest
The authors declare that they do not have any conflict of interest.
Sample collection was approved by Animal Care and Ethics Committee of the University of Miyazaki.
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