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First genetic detection and characterization of canine parvovirus from diarrheic dogs in Zambia

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Abstract

Although canine parvovirus (CPV) causes severe gastroenteritis in dogs globally, information on the molecular epidemiology of the virus is lacking in many African countries. Here, 32 fecal samples collected from diarrheic dogs in Zambia were tested for CPV infection using molecular assays. CPV was detected in 23 samples (71.9%). Genetic characterization revealed the predominance of CPV-2c (91.3%). This finding differs from previous reports in Africa, which indicated that CPV-2a and CPV-2b were most prevalent. Phylogenetically, most Zambian CPVs formed a distinct cluster. This is the first report on the molecular characterization of CPV in Zambia.

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Acknowledgements

This work was supported by the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and the Japan Agency for Medical Research and Development (AMED)/Japan International Cooperation Agency (JICA) within the framework of the Science and Technology Research Partnership for Sustainable Development (SATREPS).

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Authors and Affiliations

  1. Department of Disease Control, School of Veterinary Medicine, University of Zambia, PO Box 32379, 10101, Lusaka, Zambia

    James Kapiya, Ngonda Saasa, Martin C. Simuunza, Ayato Takada, Aaron S. Mweene & Edgar Simulundu

  2. Department of Biological Sciences, School of Natural Sciences, University of Zambia, 10101, Lusaka, Zambia

    James Kapiya & Evans Kaimoyo

  3. Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, 10101, Lusaka, Zambia

    King S. Nalubamba & Nozyechi Chidumayo

  4. Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, 10101, Lusaka, Zambia

    Katendi Changula

  5. Division of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan

    Ayato Takada

  6. Africa Center of Excellence for Infectious Diseases of Humans and Animals, 10101, Lusaka, Zambia

    Aaron S. Mweene

  7. Department of Biomedical Sciences, School of Health Sciences, University of Zambia, 10101, Lusaka, Zambia

    Simbarashe Chitanga

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  1. James Kapiya
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  2. King S. Nalubamba
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  3. Evans Kaimoyo
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  11. Edgar Simulundu
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Correspondence to Edgar Simulundu.

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Handling Editor: Sheela Ramamoorthy.

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Kapiya, J., Nalubamba, K.S., Kaimoyo, E. et al. First genetic detection and characterization of canine parvovirus from diarrheic dogs in Zambia. Arch Virol 164, 303–307 (2019). https://doi.org/10.1007/s00705-018-4068-3

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  • DOI: https://doi.org/10.1007/s00705-018-4068-3

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