Archives of Virology

, Volume 163, Issue 8, pp 2257–2260 | Cite as

Full genotype constellations of six feline Rotavirus A strains isolated in Japan in the 1990s including a rare A15 NSP1 genotype

  • Toyoko Nakagomi
  • Chantal Ama Agbemabiese
  • Osamu Nakagomi
Annotated Sequence Record


Full genome sequencing of six feline Rotavirus A (RVA) strains isolated in Japan in the 1990s revealed three genotype constellations, one of which had a unique constellation of G3-P[3]-I3-R3-C3-M3-A15-N3-T3-E3-H6. Genotype A15, carried by RVA/Cat-tc/JPN/FRV348/1994/G3P[3], is a rare NSP1 genotype, and only one human and one canine RVA strains have thus far been reported to carry this genotype. The other three G3P[3] strains (FRV72, FRV73, and FRV303) possessed a constellation of I3-R3-C2-M3-A9-N2-T3-E3-H6, whereas two G3P[9] strains (FRV317 and FRV384) possessed a constellation of I3-R3-C3-M3-A3-N3-T3-E3-H3.



The authors thank Hiroshi Masumoto for his guidance in carrying out MiSeq sequencing.


Intramural fund.

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Conflict of interest

None to declare.

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Supplementary material

705_2018_3835_MOESM1_ESM.txt (113 kb)
Supplementary material 1 (TXT 113 kb)


  1. 1.
    Estes MK, Greenberg HB (2013) Rotaviruses. In: Knipe DM, Howley PM (eds) Fields virology, 6th edn. Lippincott Williams & Wilkins, Philadelphia, pp 1347–1401Google Scholar
  2. 2.
    Matthijnssens J, Ciarlet M, Mcdonald SM, Attoui H, Bányai K, Brister JR, Buesa J, Esona MD, Estes MK, Gentsch JR, Iturriza-Gómara M, Johne R, Kirkwood CD, Martella V, Mertens PP, Nakagomi O, Parreňo V, Rahman M, Ruggeri FM, Saif LJ, Santos N, Steyer A, Taniguchi K, Patton JT, Desselberger U, Van Ranst M (2011) Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG). Arch Virol 156:1397–1413CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Matthijnssens Matthijnssens J, De Grazia S, Piessens J, Heylen E, Zeller M, Giammanco GM, Bányai K, Buonavoglia C, Ciarlet M, Martella V, Van Ranst M (2011) Multiple reassortment and interspecies transmission events contribute to the diversity of feline, canine and feline/canine-like human group A rotavirus strains. Infect Genet Evol 11:1396–1406CrossRefPubMedGoogle Scholar
  4. 4.
    Gauchan P, Sasaki E, Nakagomi T, Do LP, Doan YH, Mochizuki M, Nakagomi O (2015) Whole genotype constellation of prototype feline rotavirus strains FRV-1 and FRV64 and their phylogenetic relationships with feline-like human rotavirus strains. J Gen Virol 96:338–350CrossRefPubMedGoogle Scholar
  5. 5.
    Kaneko M, Mochizuki M, Nakagomi O, Nakagomi T (2016) Whole genome characterization of a G6P[5] rotavirus A strain isolated from a stray cat in Japan. Vet Microbiol 188:25–33CrossRefPubMedGoogle Scholar
  6. 6.
    Mochizuki M, Nakagomi O, Shibata S (1992) Hemagglutinin activity of two distinct genogroups of feline and canine rotavirus strains. Arch Virol 122:373–381CrossRefPubMedGoogle Scholar
  7. 7.
    Mochizuki M, Nakagomi T, Nakagomi O (1997) Isolation from diarrheal and asymptomatic kittens of three rotavirus strains that belong to the AU-1 genogroup of human rotaviruses. J Clin Microbiol 35:1272–1275PubMedPubMedCentralGoogle Scholar
  8. 8.
    Agbemabiese CA, Nakagomi T, Nguyen MQ, Gauchan P, Nakagomi O (2017) Reassortant DS-1-like G1P[4] Rotavirus A strains generated from co-circulating strains in Vietnam, 2012/2013. Microbiol Immunol 61:328–336CrossRefPubMedGoogle Scholar
  9. 9.
    Maes P, Matthijnssens J, Rahman M, Van Ranst M (2009) RotaC: a web-based tool for the complete genome classification of group A rotaviruses. BMC Microbiol 9:238CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Papp H, Mihalov-Kovács E, Dóró R, Marton S, Farkas SL, Giammanco GM, De Grazia S, Martella V, Bányai K (2015) Full-genome sequencing of a Hungarian canine G3P[3] Rotavirus A strain reveals high genetic relatedness with a historic Italian human strain. Virus Genes 50:310–315CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Toyoko Nakagomi
    • 1
  • Chantal Ama Agbemabiese
    • 1
  • Osamu Nakagomi
    • 1
  1. 1.Department of Molecular Epidemiology, Graduate School of Biomedical SciencesNagasaki UniversityNagasakiJapan

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