Complete genome sequence of a novel virulent phage ST31 infecting Escherichia coli H21
More and more virulent phages that are fundamental materials for phage therapy have been isolated, characterized and categorized on GenBank. Phage ST31 infecting Escherichia coli H21 was isolated from wastewater and sequenced using an Illumina Hiseq system. Opening reading frames were identified using PHASTER and predicted using BLASTp analysis. Genomic analyses revealed that this was a virulent phage containing a circular double-stranded DNA and that the complete genome consisted of 39,693 nucleotides with an average GC content of 49.98 %. This study may provide possible alternative materials for phage therapy.
We wish to thank Miss Jingnan Liang of the Institute of Microbiology, Chinese Academy of Sciences for her assistance in TEM sample preparation.
This study was funded by grant National Natural Science Foundation of China (NO. 50978250 and NO. 51378485), and the Resources and Environment Bureau of Chinese Academy of Sciences (NO.Y225018EA2).
Conflict of interest
There are not conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
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