Genotypic variability analysis of DENV-1 in Mexico reveals the presence of a novel Mexican lineage
Here, we report for the first time the circulation of dengue virus type 1 (DENV-1) belonging to the lineage IV of genotype V (African American genotype) based on phylogenetic analysis of nucleotide sequences from 10 DENV-1-positive samples obtained in Mexico between 2012 and 2014. Our data revealed that the lineages III and IV of DENV-1 genotype V were found circulating during the same period, probably explaining the rise in the number of cases of severe dengue during that period.
We would like to thank Dra. Blanca Lilia Barrón-Romero, Dra. Rosa Ma. Ahíde López-Merino, Dra. Gloria León-Ávila, Dra. Ma. Isabel Salazar-Sánchez and Dr. Cesar Hugo Hernández-Rodríguez for their encouragement of this paper, and the staff of the Laboratorio de Arbovirus and Departamento de Biología Molecular for their technical assistance. The findings and conclusions in this report are those of the authors and do not necessarily represent the official opinion of the Ministry of Health in Mexico.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants performed by any of the authors.
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