Enemies with benefits: mutualistic interactions of viruses with lower eukaryotes

Review

Abstract

Viruses represent some of the deadliest pathogens known to science. Recently they have been reported to have mutualistic interactions with their hosts, providing them direct or indirect benefits. The mutualism and symbiogenesis of such viruses with lower eukaryotic partners such as fungi, yeast, and insects have been reported but the full mechanism of interaction often remains an enigma. In many instances, these viral interactions provide resistance against several biotic and abiotic stresses, which could be the prime reason for the ecological success and positive selection of the hosts. These viruses modulate host metabolism and behavior, so both can obtain maximum benefits from the environment. They bring about micro- and macro-level changes in the hosts, benefiting their adaptation, reproduction, development, and survival. These virus-host interactions can be bilateral or tripartite with a variety of interacting partners. Exploration of these interactions can shed light on one of the well-coordinated biological phenomena of co-evolution and can be highly utilized for various applications in agriculture, fermentation and the pharmaceutical industries.

Notes

Acknowledgements

Authors acknowledge Dr. Tuli Dey, Dr. Rohan Khadilkar and Dr. Sneha Bansode for their critical comments. Authors also acknowledge Ms. Yoshita Bhide and Ms. Shriya Lele for their editorial assistance.

Author contributions

The concept was developed and articulated by SSJ and RSJ. Manuscript was written and edited by SSJ and RSJ.

Compliance with ethical standards

Conflict of interest

Authors declare no conflict of interest.

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© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Bioinformatics and BiotechnologySavitribai Phule Pune UniversityPuneIndia

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