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Novel avian leukosis viruses from domestic chicken breeds in mainland China

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Abstract

Two novel avian leukosis viruses (ALVs) were isolated from 1380 whole blood samples taken from domestic chicken breeds in China. The two ALVs were uniquely different from the env (Envelope) genes of ALV A-J and carried an LTR (long terminal repeat) cluster from ALV-E. Large scale sequence analysis further showed that these ALVs (with different env and LTRs) were recently endemic in domestic chicken breeds in both China and Japan. The emergence of these novel ALVs is challenging the current ALV eradication program, and as such novel ALVs should be monitored in a timely and careful manner to stop their transmission and further recombination in the future.

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References

  1. Payne LN, Brown SR, Bumstead N, Howes K, Frazier JA et al (1991) A novel subgroup of exogenous avian leukosis virus in chickens. J Gen Virol 72(Pt 4):801–807

    Article  PubMed  Google Scholar 

  2. Payne LN, Howes K, Gillespie AM, Smith LM (1992) Host range of Rous sarcoma virus pseudotype RSV(HPRS-103) in 12 avian species: support for a new avian retrovirus envelope subgroup, designated J. J Gen Virol 73(Pt 11):2995–2997

    Article  PubMed  Google Scholar 

  3. Payne LN, Nair V (2012) The long view: 40 years of avian leukosis research. Avian Pathol 41:11–19

    Article  CAS  PubMed  Google Scholar 

  4. Zhang QC, Zhao DM, Guo HJ, Cui ZZ (2010) Isolation and identification of a subgroup A avian leukosis virus from imported meat-type grand-parent chickens. Virol Sin 25:130–136

    Article  PubMed  Google Scholar 

  5. Zhao DM, Zhang QC, Cui ZZ (2010) Isolation and identification of a subgroup B avian leukosis virus from chickens of Chinese native breed Luhua. Bing Du Xue Bao 26:53–57

    CAS  PubMed  Google Scholar 

  6. Cui N, Su S, Chen Z, Zhao X, Cui Z (2014) Genomic sequence analysis and biological characteristics of a rescued clone of avian leukosis virus strain JS11C1, isolated from indigenous chickens. J Gen Virol 95:2512–2522

    Article  PubMed  Google Scholar 

  7. Qin A, Lee LF, Fadly A, Hunt H, Cui Z (2001) Development and characterization of monoclonal antibodies to subgroup J avian leukosis virus. Avian Dis 45:938–945

    Article  CAS  PubMed  Google Scholar 

  8. Qian K, Liang YZ, Yin LP, Shao HX, Ye JQ et al (2015) Development and evaluation of an immunochromatographic strip for rapid detection of capsid protein antigen p27 of avian leukosis virus. J Virol Methods 221:115–118

    Article  CAS  PubMed  Google Scholar 

  9. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30:2725–2729

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Chang SW, Hsu MF, Wang CH (2013) Gene detection, virus isolation, and sequence analysis of avian leukosis viruses in Taiwan country chickens. Avian Dis 57:172–177

    Article  PubMed  Google Scholar 

  11. Bowers WJ, Baglia LA, Ruddel A (1996) Regulation of avian leukosis virus long terminal repeat-enhanced transcription by C/EBP-Rel interactions. J Virol 70:3051–3059

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Hayward WS, Neel BG, Astrin SM (1981) Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature 290:475–480

    Article  CAS  PubMed  Google Scholar 

  13. Raines MA, Lewis WG, Crittenden LB, Kung HJ (1985) c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc Natl Acad Sci USA 82:2287–2291

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Gao YL, Qin LT, Pan W, Wang YQ, Le Qi X et al (2010) Avian leukosis virus subgroup J in layer chickens, China. Emerg Infect Dis 16:1637–1638

    Article  PubMed  PubMed Central  Google Scholar 

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Author information

Author notes

  1. Hongxia Shao and Lin Wang contributed equally to this work.

Authors and Affiliations

  1. Ministry of Education Key Laboratory for Avian Preventive Medicine, and Key Laboratory of Jiangsu Preventive Veterinary Medicine, Yangzhou University, 12 Wenhui East Rd, Yangzhou, 225009, Jiangsu, People’s Republic of China

    Hongxia Shao, Lin Wang, Jianjun Sang, Tuofan Li, Zhimin Wan, Kun Qian, Aijian Qin & Jianqiang Ye

  2. Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, People’s Republic of China

    Hongxia Shao, Lin Wang, Jianjun Sang, Tuofan Li, Zhimin Wan, Kun Qian, Aijian Qin & Jianqiang Ye

  3. Jiangsu Lihua Animal Husbandry Stock co. LTD, Changzhou, Jiangsu, People’s Republic of China

    Yuelong Liu

Authors
  1. Hongxia Shao
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  2. Lin Wang
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  3. Jianjun Sang
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  4. Tuofan Li
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  5. Yuelong Liu
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  6. Zhimin Wan
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  7. Kun Qian
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  8. Aijian Qin
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  9. Jianqiang Ye
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Corresponding authors

Correspondence to Aijian Qin or Jianqiang Ye.

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Funding

This work was supported by the National Key Research & Development (R&D) Plan (2016YFD0501605,2016YFD0500803), the National Natural Science Foundation of China (31472171), Key University Science Research Project of Jiangsu Province (14KJA230002), National Science and Technology Transfer Funds Project (2014GB2C100292), Six Major Talent Project in Jiangsu Province (NY-039), Cultivation of Enterprise Leader and Innovative Talents Project in Changzhou City (CQ20140005), Science and Technology Support Program in Changzhou City (CE20142015), Science and Technology Support Program in Wujin District (WN201403) and the Priority Academic Program Development of Jiangsu Higher Education Institutions.

Conflict of interest

All of the authors have no conflict of interest.

Ethical approval

The sample collection from chickens was approved by the Animal Care Committee at Yangzhou University in accordance with the institutional animal care guidelines and the protocol (#06R015).

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Shao, H., Wang, L., Sang, J. et al. Novel avian leukosis viruses from domestic chicken breeds in mainland China. Arch Virol 162, 2073–2076 (2017). https://doi.org/10.1007/s00705-017-3344-y

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  • DOI: https://doi.org/10.1007/s00705-017-3344-y

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