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G2 rotavirus within an emergent VP7 evolutionary lineage circulating in children with acute diarrhea in Guangxi Province of China, 2014

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Abstract

Routine surveillance revealed that the prevalence of P[4] rotaviruses circulating in children with acute diarrhea in Guangxi Province, China, increased in 2014. However, VP7 genotyping for these P[4] rotaviruses was unsuccessful. Exhaustive database searching and sequence analysis indicated that the G genotype of these P[4] rotaviruses was G2, and the VP7 genes clustered with recently emerging G2 strains in several countries within an emergent evolutionary lineage that was distinct from the previously designated lineages I–IV as well as lineage V including porcine rotaviruses. Further studies are essential to monitor the potential global spread of this emerging G2 rotavirus.

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Acknowledgments

This research was supported by Grants (No. Z111107056811041) from the Beijing Municipal Science and Technology Commission and the Beijing Natural Science Foundation (No. 7153159).

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Authors and Affiliations

  1. Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, 100020, China

    Hui Jin Dong, Yuan Qian, You Zhang, Lin Qing Zhao & Ru Nan Zhu

  2. Centers for Disease Control and Prevention of Guangxi Province, Nanning, 530028, Guangxi, China

    Yi Nong, Zhao Jun Mo & Rong Cheng Li

Authors
  1. Hui Jin Dong
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  2. Yuan Qian
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  3. You Zhang
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  4. Lin Qing Zhao
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  5. Ru Nan Zhu
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  6. Yi Nong
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  7. Zhao Jun Mo
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  8. Rong Cheng Li
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Corresponding author

Correspondence to Yuan Qian.

Ethics declarations

This project was approved by the Ethics Committee of the Capital Institute of Pediatrics, and no informed consent was required because the project did not reveal any personal information from the children (such as name, gender or clinical data) from whom the stool samples were collected. In addition, the stool samples used for this study were left over after routine surveillance of children with acute diarrhea at the Center for Disease Control and Prevention of Guangxi Province, China, where written informed consent was obtained, and therefore, an additional physical or financial burden was not incurred by the children or their families.

The authors declare that they have no competing interests.

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Dong, H.J., Qian, Y., Zhang, Y. et al. G2 rotavirus within an emergent VP7 evolutionary lineage circulating in children with acute diarrhea in Guangxi Province of China, 2014. Arch Virol 161, 1987–1992 (2016). https://doi.org/10.1007/s00705-016-2852-5

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  • DOI: https://doi.org/10.1007/s00705-016-2852-5

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