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Phylogeographic analysis of Japanese encephalitis virus in India (1956-2012)

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Abstract

Japanese encephalitis virus (JEV) isolates from India phylogenetically belong to two genotypes, III and I. We used envelope gene sequences from GenBank, representing different states of India and other countries, to study the spatiotemporal transmission histories of these two JEV genotypes separately. Genotype III was found to have been successively introduced in the 1930s, 1950s and 1960s, followed by genotype I twice around 2003-2006. Changes in JEV disease patterns in India over the last five decades could thus be attributed to multiple introductions of JEV strains from neighboring Asian countries along with increased transmission potential due to altered ecological settings.

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Acknowledgements

The authors are grateful to the Director, National Institute of Virology, Pune, and the Indian Council of Medical Research, New Delhi, for constant support.

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Authors and Affiliations

  1. Bioinformatics Group, National Institute of Virology, Pune, 411001, India

    Sarah S. Cherian & A. M. Walimbe

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  1. Sarah S. Cherian
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Correspondence to Sarah S. Cherian.

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Cherian, S.S., Walimbe, A.M. Phylogeographic analysis of Japanese encephalitis virus in India (1956-2012). Arch Virol 160, 3097–3104 (2015). https://doi.org/10.1007/s00705-015-2599-4

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  • DOI: https://doi.org/10.1007/s00705-015-2599-4

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