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Discovery of a novel circular DNA virus in the Forbes sea star, Asterias forbesi

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Abstract

A single-stranded DNA (ssDNA) virus, Asterias forbesi-associated circular virus (AfaCV), was discovered in a Forbes sea star displaying symptoms of sea star wasting disease (SSWD). The AfaCV genome organization is typical of circular Rep-encoding ssDNA (CRESS-DNA) viruses and is similar to that of members of the family Circoviridae. PCR-based surveys indicate that AfaCV is not clearly associated with SSWD, whereas the sea star-associated densovirus (SSaDV), recently implicated in SSWD in the Pacific, was prevalent in symptomatic specimens. AfaCV represents the first CRESS-DNA virus detected in echinoderms, adding to the growing diversity of these viruses recently recovered from invertebrates.

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Acknowledgments

This work was funded through grant DEB-1239976 from the National Science Foundation’s Assembling the Tree of Life Program to K.R and M.B. EF is funded by the Sanibel-Captiva Shell Club and Mary and Al Bridell Memorial Fellowship. This manuscript constitutes Sea Research Foundation publication #256.

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Authors and Affiliations

  1. College of Marine Science, University of South Florida, 140 7th Avenue South, Saint Petersburg, FL, 33701, USA

    Elizabeth Fahsbender, Karyna Rosario & Mya Breitbart

  2. Department of Microbiology, Cornell University, Wing Hall, 123 Wing Drive, Ithaca, NY, 14853-8101, USA

    Ian Hewson

  3. Mystic Aquarium, 55 Coogan Boulevard, Mystic, CT, 06355, USA

    Allison D. Tuttle

  4. School of Biological Sciences and Biomolecular Interaction Centre, University of Canterbury, Private Bag 4800, Christchurch, 8140, New Zealand

    Arvind Varsani

  5. Electron Microscope Unit, Division of Medical Biochemistry, Department of Clinical Laboratory Sciences, University of Cape Town, Rondebosch, Cape Town, 7701, South Africa

    Arvind Varsani

  6. Department of Plant Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, 32611, USA

    Arvind Varsani

Authors
  1. Elizabeth Fahsbender
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  2. Ian Hewson
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  3. Karyna Rosario
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  4. Allison D. Tuttle
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  5. Arvind Varsani
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  6. Mya Breitbart
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Corresponding author

Correspondence to Mya Breitbart.

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Fahsbender, E., Hewson, I., Rosario, K. et al. Discovery of a novel circular DNA virus in the Forbes sea star, Asterias forbesi . Arch Virol 160, 2349–2351 (2015). https://doi.org/10.1007/s00705-015-2503-2

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  • DOI: https://doi.org/10.1007/s00705-015-2503-2

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