Abstract
Porcine astrovirus (PAstV) is broadly distributed in pigs in several countries worldwide. PAstVs belong to the genus Mamastrovirus and are divided into five genetically divergent types. This study presents a molecular characterization of PAstV identified in diarrheic piglets in South Korea. The complete genome of the Korean PAstV strain KOR/KNU14-07/2014 was sequenced and analyzed to characterize PAstV circulating in South Korea. The full-length genomic sequence of KNU14-07 was determined to be 6,337 nucleotides in length and consisted of three major open reading frames (5′-ORF1a-ORF1b-ORF2-3′). The overall degree of nucleotide sequence identity was 40.8 to 72.5 % between KUN14-07 and other reported PAstVs, indicating high heterogeneity among PAstVs. Genetic and phylogenetic analyses showed that the KNU14-07 strain was most closely related to the PAstV2 lineage, which is the second most common type in South Korea.
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This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (2013R1A2A2A01004355).
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S. Lee and G. Jang contributed equally to this work and share co-first-authorship.
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Lee, S., Jang, G. & Lee, C. Complete genome sequence of a porcine astrovirus from South Korea. Arch Virol 160, 1819–1821 (2015). https://doi.org/10.1007/s00705-015-2436-9
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DOI: https://doi.org/10.1007/s00705-015-2436-9