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Novel circovirus in European catfish (Silurus glanis)


Circular single-stranded DNA viral genomes had been identified worldwide in different species and in environmental samples. Among them, viruses belonging to the genus Circovirus of the family Circoviridae are present in birds and pigs, and recently, they were detected in barbels. The present study reports the identification of a new circovirus in fish. PCR amplification and sequencing were used to identify the novel circular DNA virus in European catfish (Silurus glanis). Full genome characterization and phylogenetic analysis showed that the virus belonged to the family Circoviridae and that it was distantly related to the previously described barbel circovirus.

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  1. Blinkova O, Victoria J, Li Y, Keele BF, Sanz C, Ndjango JB, Peeters M, Travis D, Lonsdorf EV, Wilson ML, Pusey AE, Hahn BH, Delwart EL (2010) Novel circular DNA viruses in stool samples of wild-living chimpanzees. J Gen Virol 91:74–86

    PubMed  Article  CAS  Google Scholar 

  2. Halami MY, Nieper H, Muller H, Johne R (2008) Detection of a novel circovirus in mute swans (Cygnus olor) by using nested broad-spectrum PCR. Virus Res 132:208–212

    PubMed  Article  CAS  Google Scholar 

  3. Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser 41:95–98

    CAS  Google Scholar 

  4. Huang X, Madan A (1999) CAP3: a DNA sequence assembly program. Genome Res 9:868–877

    PubMed  Article  CAS  Google Scholar 

  5. Li L, Kapoor A, Slikas B, Bamidele OS, Wang C, Shaukat S (2010) Multiple diverse circoviruses infect farm animals and are commonly found in human and chimpanzee feces. J Virol 84:1674–1678

    PubMed  Article  CAS  Google Scholar 

  6. Li L, Shan T, Soji OB, Alam MM, Kunz TH, Zaidi SZ (2011) Possible cross-species transmission of circoviruses and cycloviruses among farm animals. J Gen Virol 92:768–772

    PubMed  Article  CAS  Google Scholar 

  7. Lőrincz M, Cságola A, Farkas SL, Székely C, Tuboly T (2011) First detection and analysis of a fish circovirus. J Gen Virol 192:1817–1821

    Article  Google Scholar 

  8. Rosario K, Duffy S, Breitbart M (2009) Diverse circovirus-like genome architectures revealed by environmental metagenomics. J Gen Virol 90:2418–2424

    PubMed  Article  CAS  Google Scholar 

  9. Rosario K, Nilsson C, Lim YW, Ruan Y, Breitbart M (2009) Metagenomic analysis of viruses in reclaimed water. Environ Microbiol 11:2806–2820

    PubMed  Article  CAS  Google Scholar 

  10. Rozen S, Skaletsky H (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132:365–386

    PubMed  CAS  Google Scholar 

  11. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28:2731–2739

    PubMed  Article  CAS  Google Scholar 

  12. Zuker M (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res 31:3406–3415

    PubMed  Article  CAS  Google Scholar 

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This study was financed in part by the Hungarian research grant OTKA K 71837 and by the Bolyai Research Fellowship of the Hungarian Academy of Sciences. The skilled help of Imre Balogh, Ágnes Juhász and Mária Ottingerné is appreciated.

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Correspondence to Tamás Tuboly.

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Nucleotide sequence data reported here are available in the GenBank database under the accession numbers JQ011377 and JQ011378.

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Lőrincz, M., Dán, Á., Láng, M. et al. Novel circovirus in European catfish (Silurus glanis). Arch Virol 157, 1173–1176 (2012).

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  • Acute Flaccid Paralysis
  • Porcine Circovirus Type
  • Ectocarpus Siliculosus
  • European Catfish
  • Major Open Reading Frame