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A comparative analysis of envelope and tegument proteins of suid herpesvirus 1, bovine herpesvirus 1 and bovine herpesvirus 5

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Abstract

The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did. Regions of disorder were found in the less conserved portions of the proteins, N-terminal and C-terminal regions, and, in a few cases, functionally important sites. The presence of DRs is an important factor in the evolution of viruses, representing points where positive pressure led to structural changes.

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Acknowledgments

Access to PONDR® was provided by Molecular Kinetics (Indianapolis, IN; 317-280-8737; E-mail: main@molecularkinetics.com). VL-XT is copyright©1999 by the WSU Research Foundation, all rights reserved. PONDR® is copyright©2004 by Molecular Kinetics, all rights reserved. We also would like to thank FAPEMIG and CNPq.

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Authors and Affiliations

  1. Laboratório de Biologia Molecular, LANAGRO/MG, Avenida Rômulo Joviano, Caixa Postal 50, Pedro Leopoldo, Brazil

    A. A. Fonseca Jr.

  2. Escola de Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627 Pampulha, Belo Horizonte, 31270-901, MG, Brazil

    M. B. Heinemann, R. C. Leite & J. K. P. Reis

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  1. A. A. Fonseca Jr.
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  2. M. B. Heinemann
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  3. R. C. Leite
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  4. J. K. P. Reis
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Correspondence to A. A. Fonseca Jr..

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Fonseca, A.A., Heinemann, M.B., Leite, R.C. et al. A comparative analysis of envelope and tegument proteins of suid herpesvirus 1, bovine herpesvirus 1 and bovine herpesvirus 5. Arch Virol 155, 1687–1692 (2010). https://doi.org/10.1007/s00705-010-0747-4

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  • DOI: https://doi.org/10.1007/s00705-010-0747-4

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