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Seroprevalence of orthopoxvirus in an Amazonian rural village, Acre, Brazil

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Abstract

Vaccinia virus strains from the family Poxviridae have been frequently isolated in Brazil and associated with outbreaks of exanthematic disease affecting cows and humans. An ELISA IgG was applied to evaluate the seroprevalence of orthopoxviruses in a community located in a rural settlement in the Amazon region, where no orthopoxvirus outbreaks have yet been reported. An overall seroprevalence of 27.89% was found, and it was 23.38% in the non-vaccinated population (smallpox vaccination). These results strongly suggest that orthopoxviruses circulate in this population, and it is the first finding of seropositivity for orthopoxviruses in a population without any previously reported outbreaks.

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Acknowledgments

The authors are grateful to Kézia K. G. Scopel, João R. dos Santos, Angela S. Lopes, Ilda M.V. Gama, Priscila A. Martins and Andreza de Carvalho. E.G.K, G.S.T P.C.P.F. and C.A.B. are recipients of research fellowships from CNPq. Financial support was provided by CNPq, MAPA, CAPES and FAPEMIG, Brazil.

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Authors and Affiliations

  1. Laboratorio de Virus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Presidente Antônio Carlos, 6627, Caixa Postal 486, Belo Horizonte, MG, 31270-901, Brazil

    B. E. F. Mota, G. S. Trindade, T. C. Diniz, G. O. L. Rodrigues, C. A. Bonjardim, P. C. P. Ferreira & E. G. Kroon

  2. Departamento de Ciências da Saúde e Educação Física, Universidade Federal do Acre, BR 364 km 04, Distrito Industrial, Rio Branco, AC, 69915-900, Brazil

    M. da Silva-Nunes

  3. Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Presidente Antônio Carlos, 6627, Caixa Postal 486, Belo Horizonte, MG, 31270-901, Brazil

    E. M. Braga

  4. Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Avenida Professor Lineu Prestes, São Paulo, SP, 05508-900, Brazil

    M. Urbano-Ferreira

Authors
  1. B. E. F. Mota
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  2. G. S. Trindade
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  3. T. C. Diniz
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  4. M. da Silva-Nunes
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  5. E. M. Braga
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  6. M. Urbano-Ferreira
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  7. G. O. L. Rodrigues
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  8. C. A. Bonjardim
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  9. P. C. P. Ferreira
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  10. E. G. Kroon
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Corresponding author

Correspondence to E. G. Kroon.

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Mota, B.E.F., Trindade, G.S., Diniz, T.C. et al. Seroprevalence of orthopoxvirus in an Amazonian rural village, Acre, Brazil. Arch Virol 155, 1139–1144 (2010). https://doi.org/10.1007/s00705-010-0675-3

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  • DOI: https://doi.org/10.1007/s00705-010-0675-3

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