Summary
The complete genome of O/Akesu/58 strain of foot-and-mouth disease virus (FMDV) was sequenced. The phylogenetic analysis revealed that it is not closely related to epidemic strains or previous strains compared with reference sequences (the identities of complete VP1 nucleotide sequences range from 77.5 to 84.0%). Its cell-receptor-binding site is a SGD (Ser-Gly-Asp) motif instead of RGD (Arg-Gly-Asp), and 43 bases were deleted in PKs region of the 5′UTR, although deletions were not found in other gene regions.
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The first two authors contributed equally to this work.
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Li, D., Liu, ZX., Bao, HF. et al. The complete genome sequence of foot-and-mouth disease virus O/Akesu/58 strain and its some molecular characteristics. Arch Virol 152, 2079–2085 (2007). https://doi.org/10.1007/s00705-007-1041-y
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DOI: https://doi.org/10.1007/s00705-007-1041-y