Summary.
Studies in transgenic mouse models of Alzheimer's disease suggested the potential for a vaccine development. However, some patients in the human clinical trials developed symptoms of brain inflammation, demonstrating the high risk of a deliberately induced auto-immune response.
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Received March 5, 2002; accepted March 12, 2002
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Münch, G., Robinson, S. Alzheimer's vaccine: a cure as dangerous as the disease?. J Neural Transm 109, 537–539 (2002). https://doi.org/10.1007/s007020200044
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DOI: https://doi.org/10.1007/s007020200044