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CID: a valid incentive delay paradigm for children

  • Psychiatry and Preclinical Psychiatric Studies - Original Article
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Abstract

Despite several modifications and the wide use of the monetary incentive delay paradigm (MID; Knutson et al. in J Neurosci 21(16):RC159, 2001a) for assessing reward processing, evidence concerning its application in children is scarce. A first child-friendly MID modification has been introduced by Gotlib et al. (Arch Gen Psychiatry 67(4): 380–387, 2010); however, comparability in the results of different tasks and validity across different age groups remains unclear. We investigated the validity of a newly modified MID task for children (CID) using functional magnetic resonance imaging. The CID comprises the integration of a more age appropriate feedback phase. We focused on reward anticipation and their neural correlates. Twenty healthy young adults completed the MID and the CID. Additionally, 10 healthy children completed the CID. As expected, both paradigms elicited significant ventral and dorsal striatal activity in young adults during reward anticipation. No differential effects of the tasks on reaction times, accuracy rates or on the total amount of gain were observed. Furthermore, the CID elicited significant ventral striatal activity in healthy children. In conclusion, these findings demonstrate evidence for the validity of the CID paradigm. The CID can be recommended for the application in future studies on reward processing in children, adolescents, and in adults.

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Acknowledgments

We thank all participants and collaborators for supporting this study.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany

    Viola Kappel, Anne Koch, Ulrike Lehmkuhl & Harriet Salbach-Andrae

  2. Clinical Psychology and Psychotherapy, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany

    Viola Kappel & Babette Renneberg

  3. Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany

    Robert C. Lorenz & Anne Beck

  4. Department of Psychology, Humboldt Universität zu Berlin, Unter den Linden 6, 10099, Berlin, Germany

    Robert C. Lorenz

  5. Physikalisch Technische Bundesanstalt Berlin, Abbestraße 2-12, 10587, Berlin, Germany

    Rüdiger Brühl

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  1. Viola Kappel
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  2. Anne Koch
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  3. Robert C. Lorenz
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Correspondence to Viola Kappel.

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Kappel, V., Koch, A., Lorenz, R.C. et al. CID: a valid incentive delay paradigm for children. J Neural Transm 120, 1259–1270 (2013). https://doi.org/10.1007/s00702-012-0962-0

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  • DOI: https://doi.org/10.1007/s00702-012-0962-0

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