Skip to main content
SpringerLink
Log in

Prevalence and treatment strategies of dyskinesia in patients with Parkinson’s disease

  • Short communication
  • Published:
Journal of Neural Transmission Aims and scope Submit manuscript

Summary

A study into the prevalence and treatment of dyskinesia in Parkinson’s disease (PD) patients was performed with 380 PD specialists-completed interviews relating to PD and retrospectively completed 1900 patient record forms for patients with dyskinesia. Physicians reported, that 34% of their PD patients experience dyskinesia, 57% of dyskinetic PD patients were affected by moderately-to-completely disabling dyskinesia. Treatment of dyskinesia was looked upon as not satisfactory, fractionating of levodopa dose was used as first choice therapeutic option of dyskinesia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • JE Ahlskog MD Muenter (2001) ArticleTitleFrequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature Mov Disord 16 448–458 10.1002/mds.1090 Occurrence Handle10.1002/mds.1090 Occurrence Handle1:STN:280:DC%2BD3MzitVCmtg%3D%3D Occurrence Handle11391738

    Article  CAS  PubMed  Google Scholar 

  • S Chapuis L Ouchchane O Metz L Gerbaud F Durif (2005) ArticleTitleImpact of the motor complications of Parkinson’s disease on the quality of life Mov Disord 20 224–230 10.1002/mds.20279 Occurrence Handle10.1002/mds.20279 Occurrence Handle15384126

    Article  PubMed  Google Scholar 

  • S Fahn D Oakes I Shoulson K Kieburtz A Rudolph A Lang CW Olanow C Tanner K Marek (2004) ArticleTitleLevodopa and the progression of Parkinson’s disease N Engl J Med 351 2498–2508 10.1056/NEJMoa033447 Occurrence Handle10.1056/NEJMoa033447 Occurrence Handle1:CAS:528:DC%2BD2cXhtVGksbnE Occurrence Handle15590952

    Article  CAS  PubMed  Google Scholar 

  • CW Olanow RL Watts WC Koller (2001) ArticleTitleAn algorithm (decision tree) for the management of Parkinson’s disease (2001): treatment guidelines Neurology 56 S1–S88 Occurrence Handle1:STN:280:DC%2BD3MzkslSlsw%3D%3D Occurrence Handle11402154

    CAS  PubMed  Google Scholar 

  • R Pahwa SA Factor KE Lyons WG Ondo G Gronseth H Bronte-Stewart M Hallett J Miyasaki J Stevens WJ Weiner (2006) ArticleTitlePractice parameter: Treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology Neurology 66 IssueID7 983–995 10.1212/01.wnl.0000215250.82576.87 Occurrence Handle10.1212/01.wnl.0000215250.82576.87 Occurrence Handle1:STN:280:DC%2BD283gtVSksQ%3D%3D Occurrence Handle16606909

    Article  CAS  PubMed  Google Scholar 

  • O Rascol DJ Brooks AD Korczyn PP De Deyn CE Clarke AE Lang M Abdalla (2006) ArticleTitleDevelopment of dyskinesias in a 5-year trial of ropinirole and L-dopa Mov Disord 21 1844–1850 10.1002/mds.20988 Occurrence Handle10.1002/mds.20988 Occurrence Handle16958094

    Article  PubMed  Google Scholar 

  • A Schrag N Quinn (2000) ArticleTitleDyskinesias and motor fluctuations in Parkinson’s disease. A community-based study Brain 123 IssueIDPt 11 2297–2305 10.1093/brain/123.11.2297 Occurrence Handle10.1093/brain/123.11.2297 Occurrence Handle11050029

    Article  PubMed  Google Scholar 

  • FP Silva-Junior P Braga-Neto MF Sueli VM de Bruin (2005) ArticleTitleAmantadine reduces the duration of levodopa-induced dyskinesia: a randomized, double-blind, placebo-controlled study Parkinsonism Relat D 11 449–452 10.1016/j.parkreldis.2005.05.008 Occurrence Handle10.1016/j.parkreldis.2005.05.008

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, St Josef Hospital, Ruhr University, Bochum, Germany

    T. Müller & D. Woitalla

  2. Merck KGaA, Darmstadt, Germany

    H. Russ, K. Hock & D. A. Haeger

Authors
  1. T. Müller
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Woitalla
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Russ
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Hock
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. A. Haeger
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Müller, T., Woitalla, D., Russ, H. et al. Prevalence and treatment strategies of dyskinesia in patients with Parkinson’s disease. J Neural Transm 114, 1023–1026 (2007). https://doi.org/10.1007/s00702-007-0718-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00702-007-0718-4

Search

Navigation