Skip to main content

Advertisement

Log in

Descriptive epidemiology of 30,223 histopathologically confirmed meningiomas in France: 2006–2015

  • Original Article
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Abstract

Background and Objectives

Meningioma is one of the most common neoplasm of the central nervous system. To describe the epidemiology of meningioma operated in France and, to assess grading and histopathological variability among the different neurosurgical centres.

Methods

We processed the French Brain Tumour Database (FBTDB) to conduct a nationwide population-based study of all histopathologically confirmed meningiomas between 2006 and 2015.

Results

30,223 meningiomas cases were operated on 28,424 patients, in 61 centres. The average number of meningioma operated per year in France was 3,022 (SD ± 122). Meningioma was 3 times more common in women (74.1% vs. 25.9%). The incidence of meningioma increased with age and, mean age at surgery was 58.5 ± 13.9 years. Grade 1, 2, and 3 meningiomas accounted for 83.9%, 13.91% and, 2.19% respectively. There was a significant variability of meningioma grading by institutions, especially for grade 2 which spanned from 5.1% up to 22.4% (p < 0.001). Moreover, the proportion of grade 2 significantly grew over the study period (p < 0.001). There was also a significant variation in grade 1 subtypes diagnosis among the institutions (p < 0.001). 89.05% of the patients had solely one meningioma surgery, 8.52% two and, 2.43% three or more. The number of surgeries was associated to the grade of malignancy (p < 0.001).

Conclusion

The incidence of meningioma surgery increased with age and, peaked at 58.5 years. They were predominantly benign with meningothelial subtype being the most common. However, there was a significant variation of grade 1 subtypes diagnosis among the centres involved. The proportion of grade 2 meningioma significantly grew over the study time, on contrary to malignant meningioma proportion, which remained rare and, stable over time around 2%. Likewise, there was a significant variability of grade 2 meningioma rate among the institutions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability

Restricted, the authors do not have permission to share data. The datasets generated and analysed for the study are not publicly available. Under French law and regulations, patient-level data from the French Brain Tumour Database cannot be made available.

Code availability

On demand.

Abbreviations

ADICAP:

Association for the Development of Information Technology in Cytology, Anatomy and Pathology

CI:

Confidence Interval

CNS:

Central Nervous System

FBTDB:

French Brain Tumour DataBase

ICD-10:

International Classification of Diseases, tenth revision

ICD-0-3:

International Classification of Diseases for Oncology, third revision

IQR:

Inter Quartile Range

PCNST:

Primary Central Nervous System Tumour

SD:

Standard Deviations

WHO:

World Health Organization

References

  1. Ammendola S, Bariani E, Eccher A, Capitanio A, Ghimenton C, Pantanowitz L, Parwani A, Girolami I, Scarpa A, Barresi V (2021) The histopathological diagnosis of atypical meningioma: Glass slide versus whole slide imaging for grading assessment. Virchows Arch 478(4):747–756

    Article  CAS  PubMed  Google Scholar 

  2. Baldi I, Gruber A, Alioum A et al (2011) Descriptive epidemiology of CNS tumors in france: Results from the gironde registry for the period 2000–2007. Neuro Oncol 13(12):1370–1378

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Bauchet L, Rigau V, Mathieu-Daudé H et al (2007) French brain tumor data bank: Methodology and first results on 10,000 cases. J Neurooncol 84(2):189–199

    Article  PubMed  Google Scholar 

  4. Brokinkel B, Hess K, Mawrin C (2017) Brain invasion in meningiomas—clinical considerations and impact of neuropathological evaluation: A systematic review. Neuro Oncol 19(10):1298–1307

    Article  PubMed  PubMed Central  Google Scholar 

  5. Champeaux-Depond C, Constantinou P, Tuppin P, Resche-Rigon M, Weller J (2022) Relative survival after meningioma surgery. A french nationwide population-based cohort study. Br J Neurosurg 1–7. https://doi.org/10.1080/02688697.2022.2159925

  6. Champeaux-Depond C, Constantinou P, Weller J (2021) Cause-specific survival after meningioma surgery: a nationwide population-based competing risk study. World Neurosurg 146:e67–e75

    Article  PubMed  Google Scholar 

  7. Champeaux-Depond C, Penet N, Weller J, Huec J-CL, Jecko V (2022) Functional outcome after spinal meningioma surgery. A nationwide population-based study Neurospine 19(1):96–107

    PubMed  Google Scholar 

  8. Champeaux-Depond C, Weller J (2021) Outcome after protontherapy for progression or recurrence of surgically treated meningioma. Brain Tumor Res Treat 9(2):46–57

    Article  PubMed  PubMed Central  Google Scholar 

  9. Champeaux-Depond C, Weller J, Constantinou P, Tuppin P, Froelich S (2022) Five-year cause-specific survival after meningioma surgery. A nationwide population-based study. Neurochirurgie 68(3):280–288

    Article  CAS  PubMed  Google Scholar 

  10. Champeaux-Depond C, Weller J, Froelich S, Resche-Rigon M (2021) A nationwide population-based study on overall survival after meningioma surgery. Cancer Epidemiol 70:101875

    Article  PubMed  Google Scholar 

  11. Champeaux-Depond C, Weller J, Froelich S, Sartor A (2021) Cyproterone acetate and meningioma: A nationwide-wide population based study. J Neurooncol 151(2):331–338

    Article  CAS  PubMed  Google Scholar 

  12. Champeaux-Depond C, Weller J, Resche-Rigon M (2020) Neurofibromatosis type 2: A nationwide population-based study focused on survival after meningioma surgery. Clin Neurol Neurosurg 198:106236

    Article  PubMed  Google Scholar 

  13. Champeaux C, Weller J, Katsahian S (2019) Epidemiology of meningiomas. A nationwide study of surgically treated tumours on french medico-administrative data. Cancer Epidemiol 58:63–70

    Article  PubMed  Google Scholar 

  14. Darlix A, Zouaoui S, Rigau V et al (2017) Epidemiology for primary brain tumors: A nationwide population-based study. J Neurooncol 131(3):525–546

    Article  CAS  PubMed  Google Scholar 

  15. Dolecek TA, Dressler EVM, Thakkar JP, Liu M, Al-Qaisi A, Villano JL (2015) Epidemiology of meningiomas post-public law 107–206: The benign brain tumor cancer registries amendment act. Cancer 121(14):2400–2410

    Article  PubMed  Google Scholar 

  16. Holleczek B, Zampella D, Urbschat S, Sahm F, von Deimling A, Oertel J, Ketter R (2019) Incidence, mortality and outcome of meningiomas: A population-based study from germany. Cancer Epidemiol 62:101562

    Article  PubMed  Google Scholar 

  17. Jecko V, Weller J, Houston D, Champeaux-Depond C (2022) Epidemiology and survival after spinal meningioma surgery: A nationwide population-based study. Asian Spine J 16(6):865–873

    Article  PubMed  PubMed Central  Google Scholar 

  18. Kshettry VR, Ostrom QT, Kruchko C, Al-Mefty O, Barnett GH, Barnholtz-Sloan JS (2015) Descriptive epidemiology of world health organization grades II and III intracranial meningiomas in the united states. Neuro Oncol 17(8):1166–1173

    Article  PubMed  PubMed Central  Google Scholar 

  19. Lang TA, Altman DG (2015) Basic statistical reporting for articles published in biomedical journals: The “Statistical Analyses and Methods in the Published Literature” or the SAMPL Guidelines. Int J Nurs Stud 52(1):5–9

    Article  PubMed  Google Scholar 

  20. Li H-Y, Ying Y-Z, Zheng D, Dong G-H, Zhang G-B, Liu X-M, Lin S, Ren X-H, Jiang Z-L (2023) Is brain invasion sufficient as a stand-alone criterion for grading atypical meningioma? J Neurosurg 139(4):953–964

    Article  PubMed  Google Scholar 

  21. Loiseau H, Huchet A, Rué M, Cowppli-Bony A, Baldi I (2009) Epidemiology of primary brain tumor. Rev Neurol (Paris) 165(8):650–670

    Article  CAS  PubMed  Google Scholar 

  22. Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO classification of tumors of the central nervous system: A summary. Neuro Oncol 23(8):1231–1251

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Ng S, Zouaoui S, Bessaoud F et al (2020) An epidemiology report for primary central nervous system tumors in adolescents and young adults: A nationwide population-based study in france, 2008–2013. Neuro Oncol 22(6):851–863

    Article  PubMed  Google Scholar 

  24. Ostrom QT, Price M, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS (2022) CBTRUS statistical report: Primary brain and other central nervous system tumors diagnosed in the united states in 2015–2019. Neuro Oncol 24:v1–v95

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Picart T, Dumot C, Guyotat J et al (2022) Clinical and pathological impact of an optimal assessment of brain invasion for grade 2 meningioma diagnosis: Lessons from a series of 291 cases. Neurosurg Rev 45(4):2797–2809

    Article  PubMed  Google Scholar 

  26. R Core Team (2014) R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna

    Google Scholar 

  27. Rigau V, Zouaoui S, Mathieu-Daudé H et al (2011) French brain tumor database: 5-year histological results on 25 756 cases. Brain Pathol 21(6):633–644

    Article  PubMed  PubMed Central  Google Scholar 

  28. Rogers L, Gilbert M, Vogelbaum MA (2010) Intracranial meningiomas of atypical (WHO grade II) histology. J Neurooncol 99(3):393–405

    Article  PubMed  Google Scholar 

  29. Rogers CL, Perry A, Pugh S et al (2016) Pathology concordance levels for meningioma classification and grading in NRG oncology RTOG trial 0539. Neuro Oncol 18(4):565–574

    Article  PubMed  Google Scholar 

  30. RStudio Team (2015) RStudio: Integrated development environment for r. RStudio Inc, Boston

    Google Scholar 

  31. Song D, Xu D, Han H, Gao Q, Zhang M, Wang F, Wang G, Guo F (2021) Postoperative adjuvant radiotherapy in atypical meningioma patients: A meta-analysis study. Front Oncol 11:787962

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Thuijs NB, Uitdehaag BMJ, Van Ouwerkerk WJR, van der Valk P, Vandertop WP, Peerdeman SM (2012) Pediatric meningiomas in the netherlands 1974–2010: A descriptive epidemiological case study. Childs Nerv Syst 28(7):1009–1015

    Article  PubMed  PubMed Central  Google Scholar 

  33. Tuppin P, Rudant J, Constantinou P et al (2017) Value of a national administrative database to guide public decisions: From the système national d’information interrégimes de l’assurance maladie (SNIIRAM) to the système national des données de santé (SNDS) in france. Rev Epidemiol Sante Publique 65(Suppl 4):S149–S167

    Article  PubMed  Google Scholar 

  34. Willis J, Smith C, Ironside JW, Erridge S, Whittle IR, Everington D (2005) The accuracy of meningioma grading: A 10-year retrospective audit. Neuropathol Appl Neurobiol 31(2):141–149

    Article  CAS  PubMed  Google Scholar 

  35. Woehrer A, Hackl M, Waldhör T et al (2014) Relative survival of patients with non-malignant central nervous system tumours: A descriptive study by the austrian brain tumour registry. Br J Cancer 110(2):286–296

    Article  PubMed  Google Scholar 

  36. Wöhrer A, Waldhör T, Heinzl H et al (2009) The austrian brain tumour registry: A cooperative way to establish a population-based brain tumour registry. J Neurooncol 95(3):401–411

    Article  PubMed  Google Scholar 

  37. Youngblood MW, Duran D, Montejo JD et al (2019) Correlations between genomic subgroup and clinical features in a cohort of more than 3000 meningiomas. J Neurosurg 1–10. https://doi.org/10.3171/2019.8.JNS191266

  38. Zouaoui S, Rigau V, Mathieu-Daudé H et al (2012) French brain tumor database: General results on 40,000 cases, main current applications and future prospects. Neurochirurgie 58(1):4–13

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

Mrs.  Segolène Van Outheusden, London, England, United Kingdom, for its manuscript review, English proofreading, grammar and spelling check. We would like thank the patients and their families. We also are grateful to all neuropathologists, neurosurgeons and other participants who helped and completed the cards for the record of PCNSTs in France. The full list of neurosurgeons and pathologists who help to build the FBTDB is provided below:

Neurosurgeons:

Abi Lahoud G., Aboukais R., Achim V., Adetchessi T., Aesch B., Agha M., Aghakhani N., Al Hallak R., Albert A., Aldea S., Ali Benali M., Ali Y., Allano V., Allaoui M., Alliez J.R., Almairac F., Aouad N., Arthuis F., Ashraf A., Assaker R., Atta M., Auque J., Autricque A., Balossier A., Barat J.L., Barnoud Croix, Baroncini M., Barral-Clavel F., Barrey C., Bataille B., Bauchet L., Baujat X., Baussart B., Bayram M., Bazin A., Beaudic Y., Beaurain J., Beccaria K., Bedou G., Bekaert O., Belaid H., Belliard H., Bellow F., Beltechi R., Ben Ismaïl M., Benazza A., Benbrahi A., Benezech J., Benhaddou-Benkirane L., Benhima H., Benmekhbi M., Bennis S., Berhouma M., Bernard C., Bernard M.H., Bernat A.L., Berthelot J.L., Besson G., Billant J.B., Billon-Grand R., Bitar A., Bizette C., Blanc J.L., Blanquet A., Blauwblomme T., Blond S., Blondet E., Boch A.L., Boetto J., Boetto S., Boissonnet H., Boniface G., Bord E., Borha A., Botella C., Bouali I., Bouazza S., Bougeard R., Bouillot P., Bouras A., Bourgeois P., Bousigue J.Y., Bousquet C., Bousquet O., Bousquet P., Boyer F., Boyer P., Brassier G., Brauge D., Bresson D., Brie, Brunon J., Buffenoir Billet K., Buisset N., Cabal P., Caillaud P., Caire F., Cam P., Cao C., Capel C., Capelle L., Cardarelli M., Carlucci L., Carpentier A., Carron R., Cebula H., Cesari J.B., Chabane A., Chabardes S., Chabolle F., Chaix R., Champeaux Depond C., Chan Seng E., Chaussemy D., Chauvet D., Chaynes P., Chays A., Chazal J., Chibbaro S., Chirossel J.P., Chivoret N., Choukri M., Civit T., Clemenceau S., Coca H.A., Cochereau J., Coll G., Colnat Coulbois S., Compaore P., Cornelius J., Cornu P., Costache D., Coste A., Coubes P., Crampette L., Cristini A., Cuny E., Curey S., Czorny A., D’acunzi G., D’hardemare V., D’houtaud S., Dagain A., Dam Hieu P., Dandine J.B., Darie I., Darrouzet V., Dauta A., Dautheribes M., David P., De Germay B., De Rose F., De Saint-Denis T., Debaux J.B., Debono B., Debry C., Decouvelaere A., Decq P., Delalande O., Delestret I., Delhaye M., Delion M., Delmas J. M., Delmotte A., Delpy P., Delsanti C., Derlon J.M., Derrey S., Desenclos C., Desgeorges M., Desplat A., Desse N., Dessi P., Destandau J., Destrieux C., Devaux B., Dezamis E., Dhellemmes P., Di Tommaso L., Diabira S., Diaz A., Dimitriu C., Djedid R., Djindjian M., Do L., Doe K., Dorel Le-The M., Dorfmuller G., Dorwling-Carter D., Dran G., Dubois G., Dudoit T., Duffau H., Dufour H., Dufour T., Duhem R., Dulou R., Dumas B., Duntze J., Dupard T., Dupuy M., Durand A., Dussartre X., Dutertre G., Duthel R., Eap C., El Fertit H., Elouahdani-Hamdi S., Emery E., Engelhardt J., Espagno C., Esposito P., Faguer R., Faillot T., Farah W., Faure A., Faure P., Ferrand Sorbets S., Fesselet J., Fichten A., Fischer D., Fischer Lokou D., Fontaine D., Fotso M.J., Fournier D., Fowo-Ngadjou S., Francois P., Frank B., Frappaz D., Freger P., Freitas Olim E., Freppel S., Froelich S., Fuentes J.-M., Fuentes S., Gaberel T., Gadan R., Gaillard S., Ganem F., Gantois C., Gauchez P., Gay M., George B., Giacomelli R., Gigaud M., Gil Robles S., Gimbert E., Ginguene C., Goasguen O., Godard J., Godfrin G., Gomez A., Gonzalez Martinez V., Gosset P., Gouello G., Goutagny S., Graillon T., Gras Combe G., Grassi M., Grayeli B., Grelat M., Grellier P., Grisoli F., Guarnieri J., Guedon, Guegan Y., Guenot M., Guerra Sierra D., Gueye E.M, Gurshi M., Guyotat J., Haddad E., Haegelen C., Hamdi S., Hamel O., Hamlat A., Hannequin P., Hansen Von Bunau F., Hatem O., Hayek G., Herbrecht A., Herman P., Hladky J.P., Hoarau X., Hoffmann D., Horodyckid C., Huot J.C., Iakovlev G., Ibrahim R., Irthum B., Ischac R., Jacquesson T., Jacquet G., James S., Jan M., Jarraya B., Jecko V., Jouanneau E., Joud A., Julhien T., Kaddoum H., Kalamarides M., Karachi C., Katrangi H., Kaya J.M., Kehrli P., Keravel Y., Khalfallah M., Khalil I., Khalil T., Khouri K., Khouri S., Kleiber J.C., Klein O., Koudsie A., Krichen W., Kuzeawu A., Laborde G., Laccoureye L., Lagarrigue J., Laguerre D., Lahiani M., Lahlou M.A., Langlois O., Lapierre F., Lapras C., Lascu, Launay O., Lavieille J.P., Le Corre M., Le Fay, Le Franc M., Le Guerinel C., Lefevre P., Legars D., Lejeune J.P., Lemaire J.J., Lena G., Lepeintre J.F., Leriche B., Leroy H.A., Lescure J.P., Leston J.M., Leveque M., Liguoro D., Lioret E., Listrat A., Litre F., Litrico S., Loiseau H., Lonjon M., Lonjon N., Lopes M., Loret J.E., Lot G., Louis E., Louveau A., Lubrano V., Lucas F., Lucas O., Lungu G., M. Dorel Le-The, Maarrawi J., Magheru C., Magro E., Maheut-Lourmiere J., Mahla K., Maillard A., Maingot M., Maisonneuve, Maitrot D., Makiese O., Mandat S., Mandonnet E., Manet R., Mansour M., Manzo N., Marchal J.C., Marie J.P., Marinho P., Marnet D., Marniche A., Martin C., Martin S., Melot A., Memia Zolo D., Mendes Martins V., Menegalli D., Menei P., Mercier P., Merlot I., Mertens P., Messerer M., Metellus P., Meyer-Bisch V., Meyer M., Mineo J.F., Mireau E., Mollier O., Monteil P., Montessuy R., Mora A., Morandi X., Morar S., Moraru C., Moreau J.J., Morel, Morel C., Mortada J., Mostofi K., Mottolese C., Moubarak K., Mourier L., Moyse E., Muckensturm B., Nader E., Nahas F., Namaki H., Narantuya K., Nataf F., Navarro S., Nebab, Nguyen J.P., Njee T., Nogues L., Noudel R., Nouet A., Nseir R., Nuti C., Orabi M., Orenstein D., Ouammou Y., Ouerchefani N., Page P., Palfi S., Pallud J., Palombi O., Paquis P., Paradot Mouton G., Parker F., Passagia J.G., Paternoster G., Pech Gourg G., Pelissou-Guyotat I., Peltier J., Pencalet P., Pencalet Ph., Penchet G., Peragut J.C., Perez A., Pernot P., Perrin G., Person H., Peruzzi P., Petit A., Petit D., Peyre M., Pimenta N.J.G., Pinelli C., Piot B., Plas B., Plas J.Y., Polo G., Popa C., Popa C.P., Porhiel V., Postelnicu A., Pouit B., Pr Vincent, Privat J.M., Proust F., Pruvot-Occean A.S., Puget S., Rabehenoina C., Rabhi M., Ragragui O., Rambolarimanana T., Ranchere, Raoul S., Rasendrarijao D., Rech F., Redondo A., Regis J., Reina V., Remond, Remond J., Reynier Y., Reyns N., Ricci Franchi A.C., Richet, Richet A., Ricouart F., Riegel T., Riem T., Riffaud L., Rigoard P., Robert G., Robert R., Robier A., Roche P.H., Rodriguez M.-A., Rodriguez V., Ros M., Roualdes G., Roualdes V., Rougier A., Roujeau T., Rousseaux P., Roux F., Roux F.X., Rue M., Sabatier J., Sabatier P., Sabbah M., Sacko O., Sainte-Rose C., Sakka L., Salaud C., Salle H., Salmon B., San Galli F., Sankaredja J.M., Sautreaux J.L., Sauvaget, Sauvaget F., Scarone P., Scavarda D., Scherpereel B., Schmidt E., Segnarbieux F., Seigneuret E., Seizeur R., Selek L., Sichez J.P., Sid Hamed S., Signorelli F., Silhouette B., Simon A., Simon E., Simonneau A., Sinardet D., Sindou M., Sleiman M., Sol J.C., Soumare O., Srour A., Srour R., Staquet H., Stecken J., Stella I., Sterkers O., Stilhart B., Szathmari A., Taha S., Tazi S., Ternier J., Testa O., Tetard M.C., Theret E., Thiebaut J.B., Thines L., Thomas C., Thomassin J.M., Tigan L., Timofeev A., Tobenas Dujardin A.C., Todeschi J., Tonnelle V., Tourneux H., Toussaint P., Touta A., Tran Ba Huy P., Travers N., Tremoulet M., Turak B., Vallee B., Vally P., Van Effenterre R., Van Raay Y., Vaneecloo F.M., Vassal F., Vassal M., Velut S., Vidal J., Vignes J.R., Villette L., Vincentelli A.F., Vinchon M., Vinikoff L., Voirin J., Wager M., Yordanova Y., Zaïri F., Zemmoura I., Zerah M., Ziyadeh J.

Pathologists:

Adam C., Adle-Biassette H., Alemany P., Algros M.P., Amat C., Andraud M., Andreiuolo F., Ansart F., Arbez-Gindre F., Arbion F., Arrivets P., Attencourt C., Aubert S., Aubriot Lorton M.H., Averous G., Aziza J., Baglin A.C., Baldet P., Bar X., Baras V., Barbey C., Bay A., Bazille C., Bedgedjian I., Bedossa P., Benabidallah S., Benali A., Bergemer Fouquet A. M., Bergouignan M.A., Bernard-Decot C., Bernier M., Bertocchi C., Beuvon F., Bielle F., Billotet C., Birembaut P., Bisiau S., Blechet C., Bondoin L., Bonneau C., Bonyhay G., Bordier X., Boudjadi S., Boulagnon-Rombi C., Boutonnat J., Bouvier C., Brambilla E., Branquet D., Breibach F., Bressenot A., Broche C., Brouchet A., Brouland J.P., Brousset P., Cabrol C., Cahn V., Calvet P., Camo J., Camparo P., Capuani C., Cassagnau E., Casse Jm., Cathelineau D., Caulet S., Caveriviere P., Cazals-Hatem D., Chambonniere M.L., Chapon F., Charlotte F., Chatelain D., Chenard M.P., Chevalier X., Chiforeanu D.C., Chretien F., Christov C., Clairotte A.,  Cohen C., Conan-Charlet V., Concha X., Cordonnier C., Cormier B., Costa K., Costa S., Costes-Charlet N., Costes V., Coulon A., Couvelard A., Croue A., Cruel T., Dag X., Danjoux M., Darrasse D., Daumas-Duport C., Del M., Delage Corre M., Delalande F., Delfour C., Delfour Ch., Delisle M.B., Delsol M., Denis-Musquer M., Deschamps L., Desestret V., Desrousseaux M., Diebold M.D., Donsbeck A.V., Dreux N., Droy-Dupre L, Dubost G., Duchesne M., Ducoin H., Dudez O., Duga I., Dumollard J.M., Durand L., Dusorbier C., Dusserre L., Duval H., Eimer S., Alami-Thomas W., Elouaret Y., Escourrou G., Etchandy C., Eyremandi R.P., Fabrice P., Fallet-Bianco C., Faroy Menciere B., Felce Dachez M., Felix S., Fernandez C., Fetissof F., Feutry C., Figarella-Branger D., Fleury C., Fontaine A., Forest F., Fornes P., Fouet B., Fregeville M., Fromont G., Gaspard C., Gauchotte G., Gay G., Godfraind C., Gontier M.F., Gonzalez S., Goujon J.M., Gray F., Gros P., Guillou P.J., Guiry C., Harimenshi J. M., Heitzmann A., Henin D., Hennequin V., Heymann M.F., Ikoli J.F., Istier L., Jazeron J.F., Jeantet M., Jouvet A., Kandel-Aznar C., Kantelip B., Kemeny J.L., Kerdraon O., Kerdraon R., Kermanac H P., Kermanac H P., Khaddage A., Kleinclaus I., Krzisch S., Kujas M., L.E., Labrousse F., Lacroix C., Lamant. L, Lantuejoul S., Laquerriere A., Laurent-Yriarte M.C., Laurent C., Le Gall F., Le Houcq M., Le Naoures-Meal C., Lechapt E., Leclair F., Leclercq, Lecointre C., Leger F., Lepreux S., Lerintiu F., Levillain P., Lhermitte B., Liprandi A., Llamas F., Llinares K., Longchampt E., Loussouarn D., Machet M.C., Maitre F., Majek-Zakine E., Manent A.M., Maran A., Marcellin L., Marchal A., Marcon N., Marcorelles P., Mareel A., Marguet C., Marie B., Martin L., Gallo M., Maues De Paula A., Maurage C.A., Mazerolles C., Mensah A., Mergey E., Meyronet D., Michalak S., Michels J.M., Michenet P., Michiels J.F., Mihlai Marcela I., Milin S., Miquel C., Mohr M., Mokhtari K., Mondon C., Monegier Du Sorbier C., Morand Dusserre I., Moreau A., Moreau M., Mos, Mosnier J.F., Musso Rigal C., Myrmel K.S., N Guyen A., Neuville A., Oksman A., Onea M.A., Pages M., Palasse J., Patey M., Pellissier J.F., Peoc’h M., Petrella T., Philippe A., Pialat J., Pluot M., Polivka M., Pommepuy I., Pradere M., Projetti F., Quintana M., Quintin I., Quintyn-Ranty M.L., Ramos J., Ranfaing E., Raoux D., Raynaud P., Reis Borges R., Renaud F., Renjard L., Reyre J., Richard P., Richard S., Rigau V., Ringenbach F., Riviere B., Roger P., Rouquette I., Rousseau A., Rousselet M.C., Rousselot C., Sabourin J.C., Saguet V., Saïkali S., Saint-Paul M.C., Saint Pierre G., Salon C., Sam, Samaison, Samaison L., Savin C., Selves J., Seurat P., Sevestre H., Singeorzan C., Sorbara R., Soulard R., Souraud J.B., Straub P., Streichenberger N., Sturm N., Szablewski V., Talagas M., Taris, Taris M., Tauziede-Espariat A., Thi N., Toquet C., Tortel M.C., Toubeau G., Tournier E., Uro-Coste E., Valmary Degano S., Vandenbos F., Varlet P., Vasiljevic A., Veresezan L., Verhulst P., Viennet G., Vignaud J.M., Vigouroux C., Villa C., Vital A., Warter A., Wassef M., Weinbreck N., Yacoub M., Zachar D., Zidane Marinnes M.

Funding

This work was conducted with the financial support of grants from the National French Institute of Cancer (INCa), la Ligue Nationale Contre le Cancer, the Committee 34, l’Association pour la Recherche sur les Tumeurs Cérébrales (ARTC et ARTC Sud), l’ANOCEF, la SFNC, le Rotary Club (AGLY), le Département de l’Hérault, and le Groupe de Neuro-oncologie du Languedoc Roussillon.

Author information

Authors and Affiliations

Authors

Consortia

Corresponding author

Correspondence to Charles Champeaux Depond.

Ethics declarations

Conflict of interest

None. The authors declare that they have no conflicts of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Depond, C.C., Zouaoui, S., Darlix, A. et al. Descriptive epidemiology of 30,223 histopathologically confirmed meningiomas in France: 2006–2015. Acta Neurochir 166, 214 (2024). https://doi.org/10.1007/s00701-024-06093-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00701-024-06093-z

Keywords

Navigation