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Intracranial posterior fossa proliferating trichilemmal tumor: first case report

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Acta Neurochirurgica Aims and scope

Abstract

Proliferating trichilemmal tumors (PTT) are rare benign lesions that predominantly occur in elderly women and usually affect the scalp. They originate from the outer root sheath of hair shafts and have trichilemmal differentiation on histopathological examination. Compared to trichilemmal cysts, PTTs show increased cell proliferation and variable cytological atypia. We report the first case of a patient with an intracranial PTT in the posterior fossa. The clinicoradiological presentation and surgical management of the patient as well as the possible pathogenesis of this tumor are discussed.

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References

  1. Berger MS, Wilson CB (1985) Epidermoid cysts of the posterior fossa. J Neurosurg 62(2):214–219

    Article  CAS  PubMed  Google Scholar 

  2. Brownstein MH (1983) Hybrid cyst: a combined epidermoid and trichilemmal cyst. J Am Acad Dermatol 9(6):872–875

    Article  CAS  PubMed  Google Scholar 

  3. Brownstein MH, Arluk DJ (1981) Proliferating trichilemmal cyst: a simulant of squamous cell carcinoma. Cancer 48(5):1207–1214

    Article  CAS  PubMed  Google Scholar 

  4. Chandler WF, Farhat SM, Pauli FJ (1975) Intrathalamic epidermoid tumor. Case report. J Neurosurg 43(5):614–617

    Article  CAS  PubMed  Google Scholar 

  5. El-Bahy K, Ishak E (2004) Trichilemmal cyst involving the skull base. Acta Neurochir (Wien) 146(12):1361–1364

    Article  CAS  PubMed  Google Scholar 

  6. Jones EW (1966) Proliferating epidermoid cysts. Arch Dermatol 94(1):11–19

    Article  CAS  PubMed  Google Scholar 

  7. Jung J, Cho SB, Yun M, Lee KH, Chung KY (2003) Metastatic malignant proliferating trichilemmal tumor detected by positron emission tomography. Dermatol Surg 29(8):872–874

    PubMed  Google Scholar 

  8. Kaido T, Okazaki A, Kurokawa S-I, Tsukamoto M (2003) Pathogenesis of intraparenchymal epidermoid cyst in the brain: a case report and review of the literature. Surg Neurol 59(3):211–221

    Article  PubMed  Google Scholar 

  9. Lobo L, Amonkar AD, Dontamsetty VV (2016) Malignant proliferating trichilemmal tumour of the scalp with intra-cranial extension and lung metastasis-a case report. Indian J Surg 78(6):493–495

    Article  PubMed  PubMed Central  Google Scholar 

  10. Netsky MG (1988) Epidermoid tumors. Review of the literature. Surg Neurol 29(6):477–483

    Article  CAS  PubMed  Google Scholar 

  11. Park BS, Yang SG, Cho KH (1997) Malignant proliferating trichilemmal tumor showing distant metastases. Am J Dermatopathol 19(5):536–539

    Article  CAS  PubMed  Google Scholar 

  12. Rengachary S, Kishore PR, Watanabe I (1978) Intradiploic epidermoid cyst of the occipital bone with torcular obstruction. Case report. J Neurosurg 48(3):475–478

    Article  CAS  PubMed  Google Scholar 

  13. Satyaprakash AK, Sheehan DJ, Sangüeza OP (2007) Proliferating trichilemmal tumors: a review of the literature. Dermatol Surg 33(9):1102–1108

    CAS  PubMed  Google Scholar 

  14. Sau P, Graham JH, Helwig EB (1995) Proliferating epithelial cysts. Clinicopathological analysis of 96 cases. J Cutan Pathol 22(5):394–406

    Article  CAS  PubMed  Google Scholar 

  15. Yamaguchi J, Irimajiri T, Ohara K (1994) Proliferating trichilemmal cyst arising in the arm of a young woman. Dermatol Basel Switz 189(1):90–92

    Article  CAS  Google Scholar 

  16. Ye J, Nappi O, Swanson PE, Patterson JW, Wick MR (2004) Proliferating pilar tumors: a clinicopathologic study of 76 cases with a proposal for definition of benign and malignant variants. Am J Clin Pathol 122(4):566–574

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurological Sciences, Christian Medical College, Vellore, India

    Pradeep Vitta, Ananth P. Abraham, Tony V. Panicker & Vivek Joseph

  2. Department of Pathology, Christian Medical College, Vellore, India

    Jonali Das

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  1. Pradeep Vitta
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  2. Ananth P. Abraham
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  3. Tony V. Panicker
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  4. Jonali Das
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  5. Vivek Joseph
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Correspondence to Vivek Joseph.

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All information is de-identified, including the radiological images and photomicrographs. We confirm that we have read the journal’s position on issues regarding ethical publication and affirm that this report is consistent with those guidelines.

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Vitta, P., Abraham, A.P., Panicker, T.V. et al. Intracranial posterior fossa proliferating trichilemmal tumor: first case report. Acta Neurochir 165, 1671–1674 (2023). https://doi.org/10.1007/s00701-023-05597-4

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  • DOI: https://doi.org/10.1007/s00701-023-05597-4

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