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Table 2 IIH patients compared to symptomatic controls

From: Cerebrospinal fluid dynamics in idiopathic intracranial hypertension: a literature review and validation of contemporary findings

  Verified IIH Symptomatic controls  
  n = 39 n = 20 p
Females 35 (89.7%) 18 (90.0%) 0.975
Mean age in years 30.2 ± 11.0 29 ± 11.6 0.808
Mean BMI (kg/m2) 36.0 ± 6.5 28.7 ± 6.5 0.001*
Mean OP (mmHg) 29.5 ± 7.7 18.5 ± 9.7 < 0.001*
Mean CSF protein count (mg/l) 299.2 ± 142.9 252.1 ± 70.9 0.247
Presenting symptoms
Headache 31 (79.5%) 18 (90.0%) 0.308
All visual symptoms 33 (84.6%) 13 (65.0%) 0.085
Tinnitus 8 (20.5%) 4 (20.0%) 0.963
Dizziness 5 (12.8%) 1 (5.0%) 0.347
Neuro-opthalmological findings at diagnosis
Optic nerve edema    
Slight 8 (20.5%) 7 (35.0%) < 0.001*
Unilateral 5 (12.8%) 1 (5.0%)  
Bilateral 26 (66.7%) 3 (15.0%)  
Visual field defects 20 (51.3%) 0 (0.0%) 0.001*
Mean visual acuity    
Right eye 1.05±0.31 1.18±0.23 0.133
Left eye 1.09±0.33 1.18±0.28 0.332
Neuroradiological findings at diagnosis
Presence of empty sella    
No 15 (42.9%) 11 (61.1%) 0.208
Yes 20 (57.1%) 7 (38.9%)  
Flattened sclera 7 (20.6%) 2 (11.1%) 0.390
Increased CSF around optic nerve 16 (47.1%) 5 (27.8%) 0.382
Intraocular protrusion of optic nerve head 2 (5.9%) 1 (5.6%) 0.962
Increased tortuosity of optic nerve 4 (11.8%) 1 (5.6%) 0.470
Neuropsychiatric findings at diagnosis
Diagnosis of psychiatric disorder (ICD-10)    
None 22 (56.4%) 15 (75.0%) 0.431
Bipolar disorder, type II (F31.8) 2 (5.1%) 0 (0.0%)  
Major depressive disorder (F33) 14 (35.9%) 5 (25.0%)  
Dissociation disorder (F44.9) 1 (2.6%) 0 (0.0%)  
  1. p Values of categorical variables from χ2 test and p values of continuous variables for ANOVA
  2. BMI body mass index, CSF cerebrospinal fluid, OP opening pressure