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Growth hormone-secreting pituitary macroadenoma presenting concurrently with non-Hodgkin’s lymphoma and responding to doxorubicin treatment: case report and review of the literature

  • Case Report - Pituitaries
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Abstract

We present a case report of a patient who presented with nausea and vomiting, as well as acromegalic features. Following testing, a pituitary adenoma and mediastinal non-Hodgkin’s lymphoma were diagnosed. Following two cycles of R-CHOP chemotherapy, imaging showed significant decrease in size of the sellar tumor. Following resection of tumor, both frozen and permanent section revealed only necrotic material. Further research into the potential utility of doxorubicin for the treatment of recurrent or refractory pituitary adenomas may be warranted.

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Correspondence to Gregory P. Lekovic.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The patient’s next of kin has consented to the submission of the case report for submission to the journal.

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This article is part of the Topical Collection on Pituitaries

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Lekovic, G.P., Batra, A., Barnard, Z.R. et al. Growth hormone-secreting pituitary macroadenoma presenting concurrently with non-Hodgkin’s lymphoma and responding to doxorubicin treatment: case report and review of the literature. Acta Neurochir 160, 2363–2366 (2018). https://doi.org/10.1007/s00701-018-3714-6

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  • DOI: https://doi.org/10.1007/s00701-018-3714-6

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