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Vanishing diffuse leptomeningeal contrast enhancement in an infant with choroid plexus papilloma

  • Case Report - Brain Tumors
  • Published:
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Abstract

Choroid plexus tumors (CPT) can present in the baseline magnetic resonance imaging (MRI) with lesions compatible with leptomeningeal dissemination. Therapeutic strategy in this condition is controversial. We present a case of an infant with CPP and significant diffuse leptomeningeal contrast enhancement at diagnosis, which spontaneously resolved after removal of the primary tumor. In these challenging cases, several aspects, such as histopathological/molecular diagnosis and close radiological follow-up, should be taken into account to avoid unnecessary treatments.

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Authors and Affiliations

  1. Department of Pediatric Neurosurgery, Hospital Sant Joan de Déu, Passeig Sant Joan de Déu 2, 08950, Esplugues de Llobregat, Barcelona, Spain

    Patricia Puerta Roldán & Antonio Guillén Quesada

  2. Neuro-Oncology Unit. Department of Pediatric Oncology, Hospital Sant Joan de Déu, Passeig Sant Joan de Déu 2, 08950, Esplugues de Llobregat, Barcelona, Spain

    Vicente Santa-María López, Andrés Morales La Madrid & Ofelia Cruz

  3. Department of Diagnostic Imaging, Hospital Sant Joan de Déu, Passeig Sant Joan de Déu 2, 08950, Esplugues de Llobregat, Barcelona, Spain

    Jordi Muchart

  4. Institute of Neuropathology, University Hospital Münster, Münster, Germany

    Christian Thomas

Authors
  1. Patricia Puerta Roldán
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  2. Vicente Santa-María López
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  3. Andrés Morales La Madrid
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  4. Ofelia Cruz
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  5. Jordi Muchart
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  6. Christian Thomas
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  7. Antonio Guillén Quesada
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Correspondence to Patricia Puerta Roldán.

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Comments

This is an interesting case report of a patient presenting with a choroid plexus tumor who also demonstrated diffuse leptomeningeal enhancement at presentation. The tumor was successfully resected. No adjuvant treatment was given. The leptomeningeal enhancement subsequently disappeared on follow-up MR imaging. The authors speculate that the enhancement may have been related to subclinical hemorrhage from the tumor. This case suggests that in the context of a low-grade choroid plexus, tumor diffuse leptomeningeal enhancement is not an indication for adjuvant therapy.

Kristian Aquilina

London, UK

This article is part of the Topical Collection on Brain Tumors

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Puerta Roldán, P., Santa-María López, V., Morales La Madrid, A. et al. Vanishing diffuse leptomeningeal contrast enhancement in an infant with choroid plexus papilloma. Acta Neurochir 161, 351–354 (2019). https://doi.org/10.1007/s00701-018-03781-5

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  • DOI: https://doi.org/10.1007/s00701-018-03781-5

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