Acta Neurochirurgica

, Volume 159, Issue 11, pp 2229–2233 | Cite as

Intrachiasmatic abscess caused by IgG4-related hypophysitis

  • Georgios F. Hadjigeorgiou
  • Eva Løbner Lund
  • Lars Poulsgaard
  • Ulla Feldt-Rasmussen
  • Åse Krogh Rasmussen
  • Marianne Wegener
  • Kåre Fugleholm
Case Report - Brain Tumors



Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.


In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.


The histologic findings were consistent with IgG4 hypophysitis.


This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.


Abscess Hypophysitis IgG4 Intrachiasmatic 


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Copyright information

© Springer-Verlag GmbH Austria 2017

Authors and Affiliations

  • Georgios F. Hadjigeorgiou
    • 1
  • Eva Løbner Lund
    • 2
  • Lars Poulsgaard
    • 3
  • Ulla Feldt-Rasmussen
    • 4
  • Åse Krogh Rasmussen
    • 4
  • Marianne Wegener
    • 5
  • Kåre Fugleholm
    • 3
  1. 1.Department of Neurosurgery, Academic Hospital Munich-BogenhausenTechnical University of MunichMunichGermany
  2. 2.Department of PathologyUniversity Hospital of CopenhagenCopenhagenDenmark
  3. 3.Department of NeurosurgeryUniversity Hospital of CopenhagenCopenhagenDenmark
  4. 4.Department of EndocrinologyUniversity Hospital of CopenhagenCopenhagenDenmark
  5. 5.Department of Neuro-opthalmologyUniversity Hospital of CopenhagenCopenhagenDenmark

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