Skip to main content
Log in

5-aminolevulinic acid (5-ALA) fluorescence in infectious disease of the brain

  • Letter to the editor - Brain Tumors
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Bissonnette R, Zeng H, McLean DI, Korbelik M, Lui H (2001) Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells. Photochem Photobiol 74(2):339–345

    Article  PubMed  CAS  Google Scholar 

  2. Colditz MJ, Jeffree RL (2012) Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 1: Clinical, radiological and pathological studies. J Clin Neurosci 19(11):1471–1474

    Article  PubMed  CAS  Google Scholar 

  3. Deorah S, Lynch CF, Sibenaller ZA, Ryken TC (2006) Trends in brain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to 2001. Neurosurg Focus 20(4):E1

    Article  PubMed  Google Scholar 

  4. Hall WA, Truwit CL (2008) The surgical management of infections involving the cerebrum. Neurosurgery 62(Suppl 2):519–530, discussion 530–531

    PubMed  Google Scholar 

  5. Kamp MA, Grosser P, Felsberg J, Slotty PJ, Steiger HJ, Reifenberger G, Sabel M (2012) 5-aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study. Acta Neurochir (Wien) 154(2):223–228, discussion 228

    Article  Google Scholar 

  6. Nestler U, Warter A, Cabre P, Manzo N (2012) A case of late-onset multiple sclerosis mimicking glioblastoma and displaying intraoperative 5-aminolevulinic acid fluorescence. Acta Neurochir (Wien) 154(5):899–901

    Article  CAS  Google Scholar 

  7. Rittenhouse-Diakun K, van Leengoed H, Morgan J, Hryhorenko E, Paszkiewicz G, Whitaker JE, Oseroff AR (1995) The role of transferrin receptor (CD71) in photodynamic therapy of activated and malignant lymphocytes using the heme precursor delta-aminolevulinic acid (ALA). Photochem Photobiol 61(5):523–528

    Article  PubMed  CAS  Google Scholar 

  8. Sharma S, Jajoo A, Dube A (2007) 5-Aminolevulinic acid-induced protoporphyrin-IX accumulation and associated phototoxicity in macrophages and oral cancer cell lines. J Photochem Photobiol B 88(2–3):156–162

    Article  PubMed  CAS  Google Scholar 

  9. Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ, for the ALA-Glioma Study Group (2006) Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicenter phase III trial. Lancet Oncol 7:392–401

    Article  Google Scholar 

  10. Tonn JC, Stummer W (2008) Fluorescence-guided resection of malignant gliomas using 5-aminolevulinic acid: practical use, risks, and pitfalls. Clin Neurosurg 55:20–26

    PubMed  Google Scholar 

Download references

Patient consent

We obtained informed consent from the patient before submission of this report.

Conflicts of interest

None.

Presentation at a conference

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Benjamin Voellger.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Voellger, B., Klein, J., Mawrin, C. et al. 5-aminolevulinic acid (5-ALA) fluorescence in infectious disease of the brain. Acta Neurochir 156, 1977–1978 (2014). https://doi.org/10.1007/s00701-014-2169-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-014-2169-7

Keywords

Navigation