Abstract
Background
Choroid plexus tumors (CPTs) are intraventricular lesions originating from ventricular neuroepithelium and represent up to 4 % of brain neoplasms affecting pediatric population. They are more frequently benign papillomas, but malignant carcinomas can sometimes occur.
Method
The authors present a description of surgical approach for CPTs, particularly focusing on the complications related to the cerebrospinal fluid (CSF) circulation, which may affect outcome.
Conclusion
Microsurgical resection represents the first line treatment for CPTs. The goal is the complete removal of the tumor and the restoration of a physiological CSF circulation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Boström A, Boström JP, von Lehe M, Kandenwein JA, Schramm J, Simon M (2011) Surgical treatment of choroid plexus tumors. Acta Neurochir (Wien) 153(2):371–376
Crocetti E, Trama A, Stiller C, Caldarella A, Soffietti R, Jaal J, Weber DC, Ricardi U, Slowinski J, Brandes A, RARECARE working group (2012) Epidemiology of glial and non-glial brain tumours in Europe. Eur J Cancer 48(10):1532–1542
Kumar R, Singh S (2005) Childhood choroid plexus papillomas: operative complications. Childs Nerv Syst 21(2):138–143
Larouche V, Huang A, Bartels U, Bouffet E (2007) Tumors of the central nervous system in the first year of life. Pediatr Blood Cancer 49(7 Suppl):1074–1082
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114(2):97–109
Madhukar M, Choudhary AK, Boal DK, Dias MS, Iantosca MR (2012) Choroid plexus: normal size criteria on neuroimaging. Surg Radiol Anat 34:887–895
Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT (2013) Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neuro-Oncol 113(1):117–125
Safaee M, Oh MC, Sughrue ME, DeLance AR, Bloch O, Sun M, Kaur G, Molinaro AM, Parsa AT (2013) The relative patient benefit of gross total resection in adult choroid plexus papillomas. J Clin Neurosci 20(6):808–812
Wolff JE, Sajedi M, Brant R, Coppes MJ, Egeler RM (2002) Choroid plexus tumours. Br J Cancer 87(10):1086–1091
Wrede B, Liu P, Wolff JE (2007) Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid plexus tumors. J Neuro-Oncol 85(3):345–351
Acknowledgments
The Authors recognise the important contribution of Roberto Faggin, M.D., and Luigi Tosatto, M.D., in the clinical management of patients.
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
(WMV 21111 kb)
Rights and permissions
About this article
Cite this article
d’Avella, D., Rossetto, M., Denaro, L. et al. Lateral ventricle’s choroid plexus tumors surgery in children: how I do it. Acta Neurochir 156, 211–215 (2014). https://doi.org/10.1007/s00701-013-1912-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00701-013-1912-9